Leg Panniculitis as the First Manifestation of Crohn’s Disease

Czech version

Authors: D. Schreiberová ¹; L. Pock ²; V. Pavlasová ¹
Authors‘ workplace: Dermatovenerologické oddělení, Nemocnice Třebíč p. o. prim. MUDr. Věra Pavlasová ¹; Schreiberová D. , Pock L. , Pavlasová V. ¹; Bioptická laboratoř Plzeň s. r. o. odborná vedoucí lékařka prof. MUDr. Alena Skálová, CSc. ²
Published in: Čes-slov Derm, 92, 2017, No. 1, p. 26-30
Category: Case Reports

Overview

Authors refer a case of a 26-year-old, otherwise healthy, man with panniculitis of lower extremities recurring for one year. Skin biopsy finding showed non-caseating granulomatous inflammation. Because of cutaneous findings and ASCA (Anti-Saccharomyces Cerevisiae Antibodies) positivity colonoscopy was performed with diagnosis of Crohn’s disease. Treatment with prednisone, mesalazine and azathioprine had no effect. Biological treatment with infliximab resulted in remission of both cutaneous symptoms and gastrointestinal involvement. Authors review current knowledge on metastatic Crohn’s disease.

Key words:
panniculitis – ASCA – Crohn’s disease – metastatic disease

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Article was published in

Czech-Slovak Dermatology

2017 Issue 1