Nimesulid-induced Severe Adverse Reaction of Generalized Bullous Fixed Drug Eruption Type – Case Report
Authors:
E. Březinová 1; V. Thon 2; S. Zgažarová 1; E. Štrnálová 1; V. Vašků 1; L. Střelec 3; R. Sís 3; H. Jedličková 1
Authors‘ workplace:
I. dermatovenerologická klinika, FN u sv. Anny a LF MU, Brno
přednosta prof. MUDr. Vladimír Vašků, CSc.
1; Ústav klinické imunologie a alergologie, FN u sv. Anny a LF MU, Brno
přednosta prof. MUDr. Jiří Litzman, CSc.
2; Oddělení psychiatricko-neurologické, Psychiatrická nemocnice Brno
primář MUDr. Ivo Černý
3
Published in:
Čes-slov Derm, 89, 2014, No. 5, p. 225-229
Category:
Case interpretation
Overview
The authors describe a case of generalized bullous fixed drug eruption after the systemic use of nimesulide successfully treated by an intravenous immunoglobulin. They discuss differential diagnoses particularly Stevens-Johnson syndrome and toxic epidermal necrolysis and provide an overview of current knowledge on the pathogenesis and treatment of this reaction.
Key words:
generalized bullous fixed drug eruption – toxic epidermal necrolysis – Stevens-Johnson syndrome – intravenous immunoglobulin – apoptosis – severe adverse drug reactions
Sources
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Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2014 Issue 5
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