#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Current Possibilities of Infantile Haemangioma Treatment


Authors: V. Novotná 1;  A. Kováčiková Curková 1;  M. Šimaljaková 1;  C. Gelmetti 2
Authors‘ workplace: Dermatovenerologická klinika LF UK a UN Bratislava, Slovenská republika prednosta prof. MUDr. Mária Šimaljaková, PhD. 1;  Department of Dermatology, University of Milan, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico Milan, Italy, prednosta prof. Carlo Gelmetti, MD, PhD. 2
Published in: Čes-slov Derm, 88, 2013, No. 2, p. 79-82
Category: Pharmacologyand Therapy, Clinical Trials

Overview

Propranolol as a pharmacological treatment of infantile haemangioma (IH) was first reported in 2008 and since then has become popular worldwide with positive clinical results and rare adverse events. IH became a new indication group for propranolol. Authors report a case of a 3-month-old child with a large infantile haemangioma of the face treated successfully with propranolol. In the submitted paper the recent knowledge about treatment of large IH with propranolol is reported, the probable mechanism of action and success of this treatment is documented in the case study.

Key words:
infantile hemangioma – pharmacological treatment – propranolol


Sources

1. CAMBIAGHI, C., GELMETTI, C. Novita in dermatologia pediatrica. Prospettive in pediatria, 2007, 37, p. 123–152.

2. De GRAAF, M., BREUR, M. J., RAPHAEL, M. F., VOS, M., BREUMGEM, C. C., PASMANS, S. G. Adverse effects of propranolol when used in the treatment of hemangiomas: a case series of 28 infants. J. Am. Acad. Dermatol., 2011, 65, p. 320–327.

3. EICHENFIELD, L. F., FRIEDEN, I. J., ESTERLY, N. B. Textbook of neonatal dermatology. W. B. Saunders Company, Philadelphia, USA, 2001, p. 324–334.

4. FABEROVA, R., BUČKOVÁ, H., FEIT, J. Hemangiomy u dětí. Čes-slov Derm., 2002, 4, s. 178–182.

5. GELMETTI, C. Diagnosi e terapia degli angiomi infantili. Prospettive in pediatria, 2001, 31, s. 287–295.

6. GREENBERGER, S., BISCHOFF, J. Infantile hemangioma – mechanism(s) of drug action on a vascular tumor. Cold Spring Harb Prospect Med., 2011, 1.

7. LANDTHALER, M., HOHENLEUNTNER, U. Zur klassifikation vascularer fehl- und neubildingen. Hautartz, 1997, 48, s. 622–628.

8. LÉAUTÉ-LABRťZE, C., DUMAS DE LA ROQUE, E., HUBICHE, T., BORALEVI, F., THAMBO, J. B., TAžEB, A. Propranolol for severe hemangiomas of infancy. Eng. J. Med., 2008, 358, 24, p. 2649–2651.

9. MOEHRLE, M., LÉAUTÉ-LABRťZE, C., SCHMIDT, V., ROCKEN, M., POETS, C. F., GOELZ, R. Topical Timolol for small hemangiomas of infancy. Pediatr Dermatol., 2012, doi: 10.1111/j.1525-1470.2012.01723.x

10. PRASBANTH, G. P. How ęunsafeę is propranolol when used in the treatment of infantile hemangioma? J. Am. Acad. Dermatol., 2012, 66, 5, p. 854–855.

Labels
Dermatology & STDs Paediatric dermatology & STDs
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#