The Significance of Diagnostic Hypoallergenic Diet in Patients with Atopic Eczema

Czech version

Authors: J. Čelakovská ¹; K. Ettlerová ²; K. Ettler ¹; J. Vaněčková ¹; J. Bukač ³
Authors‘ workplace: Klinika nemocí kožních a pohlavních FN a LF UK Hradec Králové, přednosta doc. MUDr. Karel Ettler, CSc. ¹; Ambulance klinické imunologie a alergologie, Hradec Králové, vedoucí MUDr. Květuše Ettlerová ²; Ústav lékařské biofyziky LF UK Hradec Králové, přednosta doc. Ing. Josef Hanuš, CSc. ³
Published in: Čes-slov Derm, 86, 2011, No. 3, p. 138-143
Category: Clinical and laboratory Research

Overview

Aim:
To evaluate the effect of the diagnostic hypoallergenic diet on the severity of atopic eczema in patients over 14 years of age. The diet is an important step in the diagnostic workup of the food allergy in this group of patients.

Methods:
The diagnostic hypoallergenic diet for the period of 3 weeks was recommended to patients suffering from atopic eczema. The severity of atopic eczema was evaluated at the beginning and at the end of the diet (SCORAD I, SCORAD II), the difference of SCORAD was evaluated statistically.

Results:
149 patients completed the diet: 108 females and 41 males with the average age of 26.03 (SD 9.6 years), min. 14, max. 63 years; with the median SCORAD I 32.9 points, SD 14.11 at the beginning of the study and with the median SCORAD II 25.2 points, SD 9.99 at the end of the diet. The difference between SCORAD I and SCORAD II was evaluated with Wilcoxon signed-rank test. The average decrease of SCORAD was 7.7 points and was calculated as substantial (p-value = 0.0001).

Conclusion:
On the basis of our results we recommend to introduce the diagnostic hypoallergenic diet as a temporary medical arrangement in patients suffering from moderate or severe form of atopic eczema. The diet shall serve as the important diagnostic test in the diagnostic workup of food allergy especially in those with the severe form of eczema.

Key words:
atopic eczema – diagnostic hypoallergenic diet – SCORAD

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Labels

Dermatology & STDs Paediatric dermatology & STDs

Pityriasis Rubra Pilaris

Follow-up of Patients with Melanoma

Miliaria Pustulosa

Article was published in

Czech-Slovak Dermatology

2011 Issue 3