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Cutaneous Pseudolymphomas with B-cell Predominance


Authors: L. Boudová 1;  K. Pizinger 2;  D. Kazakov 1;  O. Hes 1;  M. Michal 1
Authors‘ workplace: Šiklův patologicko-anatomický ústav FN a LF UK v Plzni, přednosta prof. MUDr. Michal Michal 1;  Dermatovenerologická klinika FN a LF UK v Plzni, přednosta prof. MUDr. Vladimír Resl, CSc. 2
Published in: Čes-slov Derm, 81, 2006, No. 2, p. 77-81
Category: Reviews (Continuing Medical Education)

Overview

Pseudolymphomas simulate lymphomas clinically and/or histologically. The differential diagnosis of lymphomas and pseudolymphomas of the skin is one of the most difficult tasks of dermatopathology. In endemic regions of Borrelia burgdorferi infection, the most common B-cell pseudolymphoma is borrelial lymphocytoma. Similar lesions might be rarely induced by vaccination, insect bite and tattoo. The differential diagnosis of skin pseudolymphomas further includes a lymphomatoid drug reaction and an inflammatory pseudotumor of the skin. Clinical, histopathological and molecular-biologic features of these lesions are summarized.

Key words:
skin – pseudolymphoma – lymphocytoma cutis – cutaneous lymphoid hyperplasia – Borrelia burgdorferi – differential diagnosis


Labels
Dermatology & STDs Paediatric dermatology & STDs
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