Authors: J. Štork 1; R. Klubal 2 Authors‘ workplace: MUDr. F. Vosmík, DrSc. 2Immunologické oddělení 2. LF UK, FN Motol, Praha přednostka doc. MUDr. J. Bartůňková, CSc. ; Kožní klinika 1. LF UK, VFN, Praha přednosta pro£ Published in: Čes-slov Derm, , 2001, No. 6, p. 311-317 Category:
Authors review retem advances in the pathogenesis of psoriasis. They highlight the role of genetic factors, keratinocytes, lymphocytes, dendritic cells and endothelial cells. Retem studies show a possible role of T-lymphocytes as cells triggering the chain of molecular and cell reactions leading to a formation of a psoriasic lesion. The critical role of T-lymphocytes is the base of provided hypothetic immunopathogenesis of psoriasis.
Key words: psoriasis - T-lymphocyte - hypothesis of immunopathogenesis
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