Complete hydatidiform mole in perimenopausal patient imitating uterine cancer

Czech version

Authors: P. Vinklerová ¹; L. Kostka ²; J. Hausnerová ³; V. Weinberger ¹
Authors‘ workplace: Gynekologicko‑porodnická klinika LF MU a FN, Brno, přednosta doc. MUDr. V. Weinberger, Ph. D. ¹; Lékařská fakulta Masarykovy univerzity, Brno, rektor prof. MUDr. M. Repko, Ph. D. ²; Ústav patologie FN Brno a LF MU, přednosta doc. MUDr. L. Křen, Ph. D. ³
Published in: Ceska Gynekol 2020; 85(5): 314-318
Category: Case Report

Overview

Case report of a perimenopausal patient with
histologically confirmed molar pregnancy, which was
imitating a malignant tumor of the uterus according to
an ultrasound examination.
Design: Case report.
Setting: Department of Obstetrics and Gynecology,
Masaryk University, University Hospital Brno.
Case report: The 51-year-old patient went to the gynecological
clinic for a month of spotting. A large tumor
was described during the ultrasound examination. It was
without an obvious invasion of the myometrium, but
significantly oppressing it. Dilatation and curettage were
indicated, which brought a surprising result – complete
hydatidiform mole. The patient wished to preserve the
uterus, so the treatment was completed by vacuum
aspiration and curettage of the uterus under ultrasound
control to remove all the rest material. The patient was
monitored at regular intervals until β-hCG negativity.
Currently, there are no signs of disease recurrence three
years after the procedure.
Conclusion: Gestational trophoblastic disease is relatively
rare in women in the peri- and postmenopausal
period, however, it is advisable to keep this diagnosis in
mind and complete β-hCG examination in the case of a
suspicious ultrasound image. Hysterectomy dominates
as the treatment method even in benign forms of the
disease. A vacuum aspiration/curettage of the uterus
with subsequent careful follow up can be alternative
option.

Keywords:

complete hydatidiform mole – gestational trophoblastic disease – perimenopausal bleeding

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