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Depressive Diseases and Multiple Sclerosis


Authors: L. Vavrušová
Authors‘ workplace: Psychiatrická klinika SZU, FNsP, Bratislava
Published in: Čes. a slov. Psychiat., 105, 2009, No. 4, pp. 173-176.
Category: Comprehensive Reports

Overview

Prevalence of depressive disorders in multiple sclerosis patients is high and is not correlated with severity of multiple sclerosis symptoms. Depressive symptoms are probably associated with the immunosuppressive treatment used. Depression remains usually unrecognized and untreated. We present a review of antidepressants available for the treatment of depression in multiple sclerosis patients and we also present an interesting case report in which many questions were raised that had to be answered by neurologist and psychiatrist in cooperation.

Key words:
multiple sclerosis, depression, antidepressants, immunosuppressants.


Sources

1. Ackerman, K. D., Rabin, B., Heyman, R., Anderson, B. P., Houch, P. R., Frank, E.: Stressful life events Precede multiple sclerosis disease exacerbations. Psychosomatic Medicine, 62, 2000, p. 147.

2. Feinstein, A., Feinstein, K.: Depression associated with multiple sclerosis. Looking beyond diagnosis to symptom expression. Journal of Affective Disorders, 66, 2001, pp. 193-198.

3. Feinstein, A.: Multiple sclerosis disease modifying treatments and depression: a critical methodological review. Multiple Sclerosis, 6, 2000, pp. 343-348.

4. Feinstein, A., O´Connor, P., Feinnstein K.: Multiple sclerosis, Interferon beta-1b and depression. J. Neurol., 24, 2002, pp. 815-820.

5. Goldman Consensus Group, Goldman Consesus statement on depression in MS. Multiple Sclerosis, 11, 2005, pp. 328-337.

6. Hart, S., Fonareva, I., Merluzzi, N., Mohr, D. C.: Treatment for depression and its relationship to improvement in quality of life and psychological well-being in multiple sclerosis patients. Quality of Life Research, 14, 2005, pp. 695-703.

7. Chwastiak, L., Ehde, D. M., Gibbons, L. E., Sullivan, M., Bowden, J. D., Kraft, G. H.: Depressive symptoms and severity of illness in multiple sclerosis: epidemiologic study of large community sample. Am. J. Psychiatry, 159, 2002, pp. 1862-1868.

8. Lisý, L.: Súčasná imunomodulačná liečba sclerosis multiplex u dospelých. Neurológia, 3, 2008, 1, s. 49-55.

9. Minden, S. L., Orav, J., Reich, P.: Depression in multiple sclerosis. General Hospital Psychiatry, 9, 1987,pp. 426-434.

10. Mohr, D. C., Goodkin, D. E., Likosky, W., Gatto, N., Baumann, K. A., Rudick, R. A.: Treatment of depression improves adherence to interferon beta-1b therapy for multiple sclerosis. Archives of Neurology, 54, 1997, pp. 531-533.

11. Mohr, D. C., Goodkin, D. E., Islar, J., Hauser, S. L., Genain, C. P.: Treatment of depression associated with supression of nonspecific and antigen-specific TH1 responses in multiple sclerosis. Archives of Neurology, 58, 2001, pp. 1081-1086.

12. Mohr, D. C., Hart, S. L., Fonareva, I., Tasch, E. S.: Treatment of depression for patients with multiple sclerosis in neurology clinics, mutiple sclerosis in neurology clinics. Multiple Sclerosis, 12, 2006, pp. 204-208.

13. Musselman, D. L., Lawson, D. H., Gumnick, J. F., Manatunga, A. K., Penna, S., Goodkin, R. S.: Paroxetine for prevention of depression induced by high-dose interferon alpha. New Engl. J. Med., 344, 2001, pp. 961-966.

14. Patten, S. B., Willliams, J. V., Love, E. J.: Self-reported depressive symptoms following treatment with corticosteroids and sedative-hypnotics. International Journal of Psychiatry in Medicine, 26, 1996, pp. 15-24.

15. Scott, T. F., Nussbaum, P., McConnel, H., Brill, P.: Measurement of treatment response to sertraline in depressed multiple sclerosis patients using the carrol scale. Neurol. Research, 17, 1995, pp. 421-422.

16. Schiffer, R. B., Wineman, N. M.: Antidepressant pharmacotherapy of depression associated with multiple sclerosis. Am. J. Psychiatry, 147, 1990, pp. 1493-1497.

17. Sollom, A. C., Kneebone, I. I.: Treatment od fepression in people who have multiple sclerosis. Multiple Sclerosis, 13, 2007, pp. 632-635.

18. Sullivan, M. J. L., Weinshenker, B., Mikail, S., Bishop, S. R.: Screening for major depression in the early stages of multiple sclerosis. Canadian Journal of Neurological Sciences, 22, 1995, pp. 228-311.

Labels
Addictology Paediatric psychiatry Psychiatry
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