Authors: M. Hrdlička; M. Blatný; T. Urbánek; M. Moráň; I. Maňasová Authors‘ workplace: Dětská psychiatrická klinika 2. LF UK a FNM, Praha, přednosta doc. MUDr. M. Hrdlička, CSc. Psychologický ústav AV ČR, Brno, ředitel doc. PhDr. I. Čermák, CSc. Neurologická klinika LF MU a FNsP Bohunice, Brno, přednosta doc. MUDr. Z. Kadaňka, CSc. Psychiat Published in: Čes. a slov. Psychiat., , 2001, No. 2, pp. 56-59. Category:
A retrospective study was implemented in females of an admission department of a psychiatrichospital. Electroconvulsive treatment was administered bilaterally by brief-pulse stimulationusing a Thymatron device. The group comprised a total of 99 female patients, mean age 47.4 ± 15.7years (range 17 - 82 years) with diagnoses of unipolar and bipolar depression, mania, schizoaffective disorders and schizophrenia. The total number of administered electroconvulsions was 663,the mean number of electroconvulsions per patient was 6.69 ± 2.24 (range 3 - 13). The total numberof electroconvulsions fit for evaluation was 657. Pharmacoresistant patients from the sub-groupof affective disorders had a generally smaller improvement of CGI (p = 0.038), the onset of the firstimprovement during treatment was later (p = 0.0008) and they needed a larger number of electroconvulsions (p = 0.014) than non-pharmacoresistent patients. In the sub-group of schizophrenicdisorders it was found that resistant patients differed significantly from non-resistant ones onlyas regards the rate of improvement of CGI (p = 0.0001).
Key words: electroconvulsive treatment, therapeutic effect, pharmacoresistance, psychopharmaceutical preparations, antidepressants, neuroleptics.
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