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Studium obsahových látek kořenu a nati Smallanthus sonchifolius pomocí plynové chromatografie – hmotnostní spektrometrie


: Olga V. Demeshko 1;  Elena V. Krivoruchko 1;  Victoria A. Samoilova 1;  Svetlana V. Romanova 2
: National University of Pharmacy, Department of Pharmacognosy 1;  National University of Pharmacy, Department of Botany 2
: Čes. slov. Farm., 2018; 67, 160-163
: Short News

Smallanthus sonchifolius (jakon) je nová perspektivní rostlina, která se v Evropě pěstuje jako přírodní náhražka cukrové třtiny. Používá se při diabetu a pro prevenci obezity. Studie karboxylových kyselin v kořenu a nati S. sonchifolius byla metodou plynové chromatografie – hmotnostní spektrometrie (GC-MS) provedena poprvé. Výsledkem studie bylo zjištění 12 složek v kořenu S. sonchifolius, z nichž devět byly karboxylové kyseliny. Nať S. sonchifolius obsahovala 41 složek, z nichž 18 byly karboxylové kyseliny. Dominantní sloučeniny v kořenu byly methylester kyseliny undecylové – 546,04 mg/kg; L-benzaziren-l-karboxylová kyselina, 2,2,5a-trimethyl-la-[3-oxo-l-butenyl] perhydro-methylester – 360,63 mg/kg; methylester kyseliny olejové – 119,21 mg/kg. V nati jakonu byl dominantní cyklohexanol, 1-ethinyl – 28,67 mg/kg.

Klíčová slova:

Smallanthus sonchifolius (jakon) • karboxylové kyseliny • GC-MS


Sources

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Pharmacy Clinical pharmacology
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