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Voltage gated calcium channels: structure, characteristics and terminology


Authors: L. Veizerová;  J. Světlík;  V. Kettmann
Authors‘ workplace: Univerzita Komenského, Farmaceutická fakulta, Katedra farmaceutickej analýzy a nukleárnej farmácie, Bratislava, Slovenská republika
Published in: Čes. slov. Farm., 2007; 56, 178-182
Category: Review Articles

Overview

Voltage-gated Ca²⁺ channels are the major pathway of Ca²⁺ entry into the cells. Their activity is essential to couple electrical signals from the cell surface to physiological events in cells. Several pharmacologically, structurally and kinetically distinct calcium channel types have been identified at the electrophysiological and molecular levels. This review aims to describe the functional, structural and pharmacological properties of voltage-gated calcium channels.

Key words:
voltage-dependent Ca²⁺ channels – types of calcium channel proteins – electrophysiology – terminology – subunits


Labels
Pharmacy Clinical pharmacology
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