Authors: R. Masteiková; R. Bernatonienė 1; A. Savickas 2; Z. Chalupová; J. Bernatonienė 2 Authors‘ workplace: Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav technologie léků ; Kaunasská univerzita medicíny Litva, Farmaceutická fakulta, Katedra farmaceutické chemie a farmakognozie 1; Kaunasská univerzita medicíny Litva, Farmaceutická fakulta, Katedra technologie léků a sociální farmacie 2 Published in: Čes. slov. Farm., 2006; 55, 268-271 Category: Original Articles
The paper aimed to elaborate the technology of the production of a liquid ginger extract and to select and verify the methods of quality evaluation of the final preparation. The experiment revealed 70% ethanol as a suitable extraction agent. The optimal conditions for the development of an extract of good quality are established when the herbal drug is crushed to form particles passing through a sieve with a mesh size of 4000 μm, the extraction method is repercolation with the division of the charge of the drug in the relation 5 : 3:2, and the liquid flows from the percolator at a rate of 0.2ml/min/100 g of the drug. The presence of amino acids, saccharides, glycosides, reducing agents, phenolic substances, and alkaloids in the finished extract was demonstrated by means of colour or precipitation reactions. Thin-layer chromatography was employed to demonstrate gingerols and shogaols. Evaporation residue, ethanol concentration, and the amount of essential oils were determined quantitatively.
Key words: Zingiber officinale – liquid extract – technology – evaluation
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