Authors: I. Malík; E. Sedlárová; J. Čižmárik; F. Andriamainty; J. Csöllei 1 Authors‘ workplace: Farmaceutická fakulta Univerzity Komenského v Bratislave, Katedra farmaceutickej chémie, SR ; Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav chemických léčiv 1 Published in: Čes. slov. Farm., 2005; 54, 235-239 Category: Original Articles
The paper presents the study of some physicochemical properties of 2-, 3-, 4-alkoxy - phenylcarbamic acid derivatives with various substituted N-phenylpiperazin-1-yl moiety in the basic part of the molecule. Elemental analysis, melting point, solubility, surface activity, dissociation constant and some lipophilicity parameters i.e. – partition coefficient, capacity factor obtained from HPLC, and RM values from reversed-phase thin-layer chromatography were determined.
Key words: substituted N-phenylpiperazine moiety – physicochemical properties – phenylcarbamates
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