Adsorption of Substances on Active Charcoal – Part 3: Stobadin Acylderivatives
Authors:
M. Stankovičová; Ĺ. Stráska; K. Záreczká; Ž. Bezáková; L. Bene· 1; Farmaceutická Fakulta Univerzity Komenského V Bratislave; Katedra Farmaceutickej Chémie; Farmaceutická Fakulta Veterinární 1; Farmaceutické Univerzity Brno; Ústav Chemických Léčiv
Published in:
Čes. slov. Farm., 2005; 54, 60-64
Category:
Original Articles
Overview
The paper studies the adsorption of nine stobadin acylderivatives on active charcoal. Freundlich model of adsorption was employed to evaluate the course of adsorption in dependence on the concentration of substances. At the same time, the dependence of adsorption on lipophilicity and structural parameters of substances was evaluated. The dependence of the amount of the adsorbed substance on time served for the calculation of the rate constant of the 1st order of adsorption process. These values correlate with the parameters characterizing the size of the molecule.
Key words:
stobadin acylderivatives – stobadin – adsorption on active charcoal
Labels
Pharmacy Clinical pharmacologyArticle was published in
Czech and Slovak Pharmacy
2005 Issue 2
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