Advances in the Development of Antituberculotics Containing No Heterocycles in thePharmacophorePart 2. Other Derivatives Except Carboxylic Acids

Overview

This paper is the 21st communication in the series of review papers on the development ofantituberculotics and the 10th communication summarizing the papers on the development ofantituberculotics in recent 15 years. The first seven communications were devoted to heterocycliccompounds, the eighth one to the compounds containing an alkylsulfanyl group in the pharmacophore.The present paper sums up information concerning the compounds not containing a heterocyclein the pharmacophore which are not derivatives of carboxylic acids either. This completes theseries of communications recording the development of antituberculotics in the recent period. Thecommunication records papers published since 1980 because it intends to link up with a reviewpaper puslished in 1982 (Českoslov. Farm., 1982; 31, 353–360).

Key words:
tuberculostatics – mycobacteria – Mycobacterium tuberculosis