Authors: J. Kolčák; M. Stuchlík; M. Rabišková 1 Authors‘ workplace: IVAX-CR, Opava-Komárov, 1Ústav technologie léků Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno Published in: Čes. slov. Farm., 2003; , 4-11 Category:
Soft gelatin capsules are a dosage form suitable particularly for administration of sensitive drugsposing technological problems. They mask an unpleasant taste or smell of the drug and the colourcombinations increase the safety of therapy by excluding interchangings. Their manufacture isundemanding, it depends on the quality of gelatin and the gelatin mass for the shell of the capsules,on the properties of the fill, on mutual interactions between the fill and the shell, and on a specialknow-how, which is an unconditional precondition of successful manufacture of this dosage formThe paper is a review characterizing soft gelatin capsules, processes of their manufactures, andquality evaluation.
Key words: soft gelatine capsules – capsule fill – capsule shell – processes of manufacture –evaluation – biological availability of drug
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