Radiation-Induced Meningiomas

Czech version

Authors: R. Jančálek ¹; Z. Novák ¹; J. Chrastina ¹; B. Slaná ²; V. Feitová ³
Authors‘ workplace: LF MU a FN u sv. Anny v Brně Neurochirurgická klinika ¹; LF MU a FN u sv. Anny v Brně I. patologicko-anatomický ústav ²; LF MU a FN u sv. Anny v Brně Klinika zobrazovacích metod ³
Published in: Cesk Slov Neurol N 2011; 74/107(2): 191-196
Category: Short Communication

Overview

Radiotherapy has recently become a standard procedure for the treatment not only of high-grade intracranial tumours but also of some of benign nature. Despite its therapeutic potential, radiotherapy can act as a trigger for carcinogenesis. Meningiomas are the most frequent intracranial tumours induced by radiotherapy because the radiosensitivity of meningeal tissue is high. Radiation-induced meningiomas differ from spontaneous meningiomas in their higher incidence in younger age groups. They are also more frequently multiple with histological abnormalities and a higher incidence of recurrence. First-choice therapy for radiation-induced meningiomas is surgical. Stereoradiosurgery appears to be the treatment of choice for progressive meningiomas in locations inaccessible to surgical approach. Three cases of radiation-induced meningiomas were found in a retrospective study of patients treated at the Department of Neurosurgery, St. Anne’s University Hospital, Brno. In conclusion, radiation-induced meningiomas form a specific group. Their specific features should be borne in mind in the course of oncology care.

Key words:
radiation-induced meningiomas – features – therapy

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