Benefits and risks of primary prevention of venous thromboembolism in the elderly

Czech version

Authors: D. Weberová; H. Matějovská Kubešová; P. Weber
Authors‘ workplace: Klinika interní, geriatrie a praktického lékařství LF MU a FN Brno
Published in: Kardiol Rev Int Med 2018, 20(1): 36-40

Overview

Venous thromboembolism is a relatively common cardiovascular disease with a comparatively high morbidity and mortality. It includes two principal units – deep venous thrombosis and pulmonary embolism. The incidence and prevalence of venous thromboembolism increase exponentially with age. Therefore, there is no doubt about the importance of age as one of the principal risk factors causing this disorder. With increasing life expectancy, the relative and absolute numbers of patients suffering from this illness increases and will increase. Furthermore, geriatric patients show specific clinical signs, frequently suffer from polymorbidity and use polypharmacy. Therefore, they present a vulnerable group tending to develop venous thromboembolism with a higher risk of severe consequences as compared to younger adults. Accordingly, it is of high importance to primarily prevent venous thromboembolism in older patients considering their vulnerability to coagulability as well as to bleeding.

Key words:
venous thromboembolism – deep venous thrombosis – pulmonary embolism – prophylaxis – elderly patients – NOAC – polymorbidity – polypharmacotherapy

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