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The impact of rheumatic diseases on cardiovascular risk and lipidogram

Czech version

Authors: Vladimír Bláha
Authors‘ workplace: III. interní gerontometabolická klinika LF UK a FN Hradec Králové
Published in: AtheroRev 2018; 3(2): 126-132
Category: Reviews

Overview

Long-term mortality in rheumatic diseases is caused mainly by increased cardiovas­cular risk, which cannot be explained only by traditional risk factors. Rheumatic disease seems to be an independent  cardiovascular risk factor, which is influenced mainly by the type of therapy of rheumatic disease, blood lipid concentration and the magnitude of systemic inflammation. Moreover, lipid paradox plays a role, i.e. increased cardiovascular risk associates with lower total cholesterol, but low LDL-C does not mean reduced cardiovascular risk. To minimize cardiovascular risk of rheumatic patients the action for optimal control of the rheumatic disease activity, regular evaluation of cardio­vascular risk, screening for asymptoma­tic atherosclerosis and implementation of appropriate dietary, regime and therapeutical arrangements using hypolipidemic therapy, mainly by statins, is needed.

Key words:

atherosclerosis, cardiovascular disease, cardiovascular risk, hypercholesterolemia, LDL-cholesterol, rheumatoid arthritis, psoriatic arthritis, spondyloarthritis

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