Bee’s honey in the process of wound healing
Authors:
Juraj Majtán 1,2; Alexander Mayer 3; Miroslava Horniačková 2; Viktor Majtán 2; Juraj Olejník 3
Authors‘ workplace:
Ústav Zoológie SAV, Bratislava
1; Oddelenie mikrobiológie, Lekárska fakulta SZU, Bratislava
2; Chirurgická klinika SZU a FNsP, Nemocnica akad. L. Dérera, Bratislava
3
Published in:
Hojení ran 7, č. 3: 3-6, 2013
Category:
Bee’s honey in wound healing
Overview
Bee’s honey is a natural product with antibacterial and immunomodulating properties that fulfils the concept of an ideal tool in the process of healing of chronic wounds. The main advantage of the honey is its multifactorial antibacterial activity and the fact thatbacteria cannot develop a resistance to the honey. The honey and its individual components are able to both stimulate and inhibit the production of cytokines (TNF-α, IL-1β a IL-6) of monocytes and macrophages depending on the surrounding conditions as well as accelerate the process of re-epitelisation by a stimulation of the proliferation and migration of cutaneous cells (keratinocytes and fibroblasts).
Detailed characterization of biological effects of the honey will facilitate its wider use in clinics and greater concern in the community of medical specialists about the wound treatment with natural products.
Key words:
honey, wound healing, immunomodulation, antibacterial action
Sources
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Wound Healing
2013 Issue 3
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