Systemic toxic effects of Mesocain® in routine surgical practice upon iatrogenic overdose requiring cardiopulmonary resuscitation – case report

Czech version

Authors: J. Šimek ^1,3; K. Šmejkal ^1,3; M. Jakl ²; J. Trlica ^1,3
Authors‘ workplace: Katedra vojenské chirurgie, Fakulta vojenského zdravotnictví Hradec Králové, Univerzita obrany v Brně, Česká republika ¹; Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Hradec Králové, Česká republika ²; Chirurgická klinika, Fakultní nemocnice Hradec Králové, Česká republika ³
Published in: Rozhl. Chir., 2023, roč. 102, č. 6, s. 257-260.
Category: Case Reports
doi: https://doi.org/10.33699/PIS.2023.102.6.257–260

Overview

This case report of a patient with a traumatic head injury provides an example of a systemic toxic reaction to a local anesthetic. Clinical signs of a systemic toxic reaction and hemorrhagic shock may initially be similar: tachycardia, hypotension and unconsciousness. The purpose is thus to remind that even the treatment of a minor injury can develop into a life-threatening condition. When a skin wound is treated using suture under local or regional anesthesia, the annual incidence rate of systemic toxic reactions is 1:3,000 and that of death is 1:30,000.

Keywords:

anaphylaxis – mesocain – trimecain – toxic reaction

Sources

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Article was published in

Perspectives in Surgery

2023 Issue 6