Severe autoimune thyreotoxicosis complicated by febrile neutropenia as a result of thyreostatic therapy
Authors:
Marie Jarolímová; Michal Kazmíř
Authors‘ workplace:
Interní oddělení, Oblastní nemocnice Kolín, a. s.
Published in:
Vnitř Lék 2023; 69(E-2): 19-22
Category:
Case reports
doi:
https://doi.org/10.36290/vnl.2023.024
Overview
Hyperthyreoidism is a clinical manifestation of excessive production of thyroid hormones. In most cases pacient ´s condition allows ambulant treatment. Rarely, it can develop into an acute, life- threatening thyrotoxic crisis which has to be treated in the intensive care unit. Main therapy includes antithyroid medication, corticosteroids, beta- blockers and rehydratation, mostly parenteral. If initial treatment fails, plasmapheresis provides effective strategy.
Antithyroid medication may come with side effects as rash, digestive issues, joint pain.Agranulocystosis or acute liver lesion which leads to liver failure belong among the most severe ones. In this case we report a pacient with thyrotoxic crisis, atrial fibrilation which led to ventricular fibrilation, cor thyreotoxicum. The treatment was complicated by febrile neutropenia.
Keywords:
agranulocytosis – hyperthyreoidism – Lugol solution – total thyreoidectomy – thyrotoxic crisis
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Labels
Diabetology Endocrinology Internal medicineArticle was published in
Internal Medicine
2023 Issue E-2
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