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proLékaře.cz / Journals / Internal Medicine / 2018 - 10

Transient elastography – role in the assessment of the liver disease development

Czech version

Authors: Nikola Uzlová 1;  Nikola Mejzlíková 1;  Soňa Fraňková 2;  Pavla Libicherová 1;  David Nosek 1;  Ivan Rychlík 1
Authors‘ workplace: I. interní klinika 3. LF UK a FN Královské Vinohrady, Praha 1;  Klinika hepatogastroenterologie IKEM, Praha 2
Published in: Vnitř Lék 2018; 64(10): 916-922
Category:

Overview

Transient elastography, an examination based on the liver stiffness measurement, is a method validated for the non-invasive liver fibrosis staging. This method was recently successfully introduced into routine clinical practice. In accordance with the global- wide screening of viral hepatitis (chronic viral hepatitis type B and type C) and with the increasing effectiveness of antiviral therapy, as well as with the increasing prevalence of non-alcoholic fatty liver disease (NAFLD), the part of population requiring the care of hepatologists is certain to increase. Now more than ever we need a non-invasive, fast, safe, inexpensive and reliable method for evaluating patients with chronic liver disease. A new area of ​​use of elastography appears to be used to measure the stiffness of the spleen as a prediction of the presence of esophageal varices or the stiffness (or rather fibrosis) of transplanted kidneys. The aim of this review is to provide a comprehensive view of transient elastography, its principles, advantages and pitfalls, including its use in everyday clinical practice.

Key words:

cirrhosis – fibrosis – renal allograft – transient elastography

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