Diabetes mellitus and cognitive disorders from the diabetologist’s perspective

Czech version

Authors: Alena Šmahelová
Authors‘ workplace: III. interní gerontometabolická klinika LF UK a FN Hradec Králové
Published in: Vnitř Lék 2017; 63(10): 717-720
Category: Reviews

Overview

Diabetes mellitus is associated with cognitive impairment which may convert to vascular or neurodegenerative dementia. Impairment of cognitive functions affects patients with type 1 and especially type 2 diabetes, with a number of vascular, metabolic and psychosocial factors involved in its development. As hyperglycemia and hypoglycemia also play an important role, important is the correct strategy of diabetes therapy which utilizes a combination of metformin with modern safe antidiabetics (incretin drugs, gliflozins, insulin analogues). It seems that some antidiabetic drugs (metformin, incretin drugs) and nasal form of application of insulin could improve cognition in diabetics.

Key words:
antidiabetic drugs – diabetes mellitus – hyperglycemia – hypoglycemia – cognition

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