Unusual lung finding of massive alveolar filling with foamy macrophages in congenital epidermolysis bullosa after amnion fluid aspiration in 15-day-old newborn without any clinical signs of respiratory impairment
Authors:
Daniel Farkaš 1; Marián Švajdler ml. 2; Lucia Fröhlichová 2; Jana Šprláková 3; Silvia Farkašová Iannaccone 4; Zoltán Szép 5; Oľga Nyitrayová 5
Authors‘ workplace:
Bioptická laboratoř s. r. o., Plzeň, Česká Republika
a Oddelenie patológie, Univerzitná nemocnica Louisa Pasteura, Košice, Slovenská Republika
; Úrad pre dohľad nad zdravotnou starostlivosťou, SLaPA pracovisko, Košice
1; Šiklův ústav patologie, Univerzita Karlova Praha, Lékařská fakulta Plzeň, Česká Republika
2; Detská fakultná nemocnica, Košice
3; Ústav súdneho lekárstva UPJŠ LF, Košice
4; Cytopathos s. r. o., Bratislava
5
Published in:
Čes.-slov. Patol., 51, 2015, No. 2, p. 89-93
Category:
Original Article
Overview
Epidermolysis bullosa represents a group of mechanobullous diseases which are most commonly genetically determined. We describe the case of a 15-day-old female newborn with congenital epidermolysis bullosa which was inflicted on aproximately 1/3 of her skin surface, who died because of incorrigible sepsis with multiorgan failure. The main topic of our report is a description of an unusual pulmonary finding of massive alveolar filling with foamy macrophages after amnion fluid aspiration, which contained a excessive amount of desquamated epidermal cells. Introduced case shows outstanding discrepancy of negative clinical finding on one side and massive histopathological finding on the other.
Keywords:
epidermolysis bullosa – foamy alveolar macrophages – amniotic fluid aspiration
Sources
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
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