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Prevalence of spondyloarthritis in patients with acute anterior uveitis

Czech version

Authors: K. Bubová 1,2;  J. Heissigerová 3;  L. Šenolt 1,2
Authors‘ workplace: Revmatologický ústav Praha 1;  Revmatologická klinika 1. LF UK, Praha 2;  Oční klinika 1. LF UK a VFN, Praha 3
Published in: Čes. Revmatol., 30, 2022, No. 3, p. 114-120.
Category: Review Article

Overview

Spondyloarthritis (SpA) is the most common systemic inflammatory disease associated with acute anterior uveitis (AAU). There are many works that have addressed the prevalence of AAU in patients with SpA; however, information on the prevalence of SpA and its individual symptoms in patients with AAU is limited. Our work aimed to unify published data on this topic. According to recent studies, the prevalence of axial SpA (axSpA) in patients with AAU is around 40%, while the prevalence of peripheral forms of SpA is lower. The most common finding is the presence of sacroiliitis, which, however, also occurs in completely asymptomatic patients with AAU. Enthesitis and possibly peripheral arthritis are also common symptoms. At the same time, patients with AAU and associated SpA have higher levels of systemic inflammatory parameters, more frequent back pain, and worse mobility of the spine than patients without associated SpA. No difference in ocular symptomatology was found. AAU as the first clinical symptom of SpA represents the possibility of earlier detection of this potentially disabling disease. Referral strategies for ophthalmologists will be discussed. Due to the close connection between these two diseases, tight cooperation between ophthalmologists and rheumatologists is necessary.

Keywords:

axial spondyloarthritis – acute anterior uveitis – spondyloarthritides

Sources
  1. Cantini F, Nannini C, Cassarà E, Kaloudi O, Niccoli L. Uveitis in spondyloarthritis: an overview. J Rheumatol Suppl 2015; 93: 27–29.
  2. Chen B, Li J, He C, Li D, Tong W, Zou Y, et al. Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review). Mol Med Rep 2017; 15(4): 1943–1951. 
  3. D’Ambrosio EM, La Cava M, Tortorella P, Gharbiya M, Campanella M, Iannetti L. Clinical features and complications of the HLAB27- associated acute anterior Uveitis: a metanalysis. Semin Ophthalmol 2017; 32(6): 689–701.
  4. Bengtsson K, Forsblad-d’Elia H, Deminger A, Klingberg E, Dehlin M, Exarchou S, et al. Incidence of extra-articular manifestations in ankylosing spondylitis, psoriatic arthritis and undifferentiated spondyloarthritis: results from a national register-based cohort study. Rheumatology (Oxford) 2021; 60(6): 2725–2734
  5. Robinson PC, Claushuis TA, Cortes A, Martin TM, Evans DM, Leo P, et al. Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis. Arthritis Rheumatol 2015; 67(1): 140–151.
  6. Zeboulon N, Dougados M, Gossec L. Prevalence and characteristics of uveitis in the spondyloarthropathies: a systematic literature review. Ann Rheum Dis 2008; 67(7): 955–959.
  7. Sieper J, Poddubnyy D. Axial spondyloarthritis. Lancet 2017; 390(10089): 73–84.
  8. Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkoc N, Brandt J, et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 2009; 68(6): 777–783.
  9. Poddubnyy D, Rudwaleit M, Haibel H, Listing J, Marker-Hermann E, Zeidler H, et al. Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis. Ann Rheum Dis 2011; 70(8): 1369–1374.
  10. Tay-Kearney ML, Schwam BL, Lowder C, Dunn JP, Meisler DM, Vitale S, et al. Clinical features and associated systemic diseases of HLA-B27 uveitis. Am J Ophthalmol 1996; 121(1): 47–56.
  11. Monnet D, Breban M, Hudry C, Dougados M, Brézin AP. Ophthalmic findings and frequency of extraocular manifestations in patients with HLA-B27 uveitis: a study of 175 cases. Ophthalmology 2004; 111(4): 802–809.
  12. Linssen A, Meenken C. Outcomes of HLA-B27-positive and HLA-B27-negative acute anterior uveitis. Am J Ophthalmol 1995; 120(3): 351–361.
  13. Bubova K, Hasikova L, Mintalova K, Gregova M, Kasalicky P, Klimova A, et al. The prevalence of MRI-defined sacroiliitis and classification of spondyloarthritis in patients with acute anterior uveitis: a Longitudinal single-centre cohort study. Diagnostics (Basel) 2022; 12(1).
  14. Oliveira TL, Maksymowych WP, Lambert RGW, Muccioli C, Fernandes ARC, Pinheiro MM. Sacroiliac joint Magnetic resonance imaging in asymptomatic patients with recurrent acute anterior uveitis: a proof-of-concept study. J Rheumatol 2017; 44(12): 1833–1840.
  15. Juanola X, Loza Santamaría E, Cordero-Coma M. Description and prevalence of spondyloarthritis in patients with anterior uveitis: The SENTINEL Interdisciplinary Collaborative Project Ophthalmology 2016; 123(8): 1632–1636.
  16. Sykes MP, Hamilton L, Jones C, Gaffney K. Prevalence of axial spondyloarthritis in patients with acute anterior uveitis: a cross- -sectional study utilising MRI. RMD Open 2018; 4(1): e000553.
  17. Haroon M, O’Rourke M, Ramasamy P, Murphy CC, FitzGerald O. A novel evidence-based detection of undiagnosed spondyloarthritis in patients presenting with acute anterior uveitis: the DUET (Dublin Uveitis Evaluation Tool). Ann Rheum Dis 2015; 74(11): 1990–1995.
  18. Chung YM, Liao HT, Lin KC, Lin YC, Chou CT, Chen CH, et al. Prevalence of spondyloarthritis in 504 Chinese patients with HLA-B27-associated acute anterior uveitis. Scand J Rheumatol 2009; 38(2): 84–90.
  19. Dougados M, Linden SVD, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondylarthropathy Study Group Preliminary Criteria for the Classification of Spondylarthropathy. Arthritis & Rheumatism 1991; 34(10): 1218–1227.
  20. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984; 27(4): 361–368.
  21. Sieper J, van der Heijde D, Landewe R, Brandt J, Burgos-Vagas R, Collantes-Estevez E, et al. New criteria for inflammatory back pain in patients with chronic back pain: a real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Ann Rheum Dis 2009; 68(6): 784–788.
  22. Muñoz-Fernández S, de Miguel E, Cobo-Ibáñez T, Madero R, Ferreira A, Hidalgo MV, et al. Enthesis inflammation in recurrent acute anterior uveitis without spondylarthritis. Arthritis Rheum 2009; 60(7): 1985–1990.
  23. de Azevedo Fraga NA, de Fátima Oliveira M, Follador I, de Oliviera Rocha B, Rêgo VR. Psoriasis and uveitis: a literature review. An Bras Dermatol 2012; 87(6): 877–883.
Labels
Dermatology & STDs Paediatric rheumatology Rheumatology
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