Constituents of the leaves of Cornus officinalis Sieb. et Zucc.
Authors:
Vladimír Forman; Daniel Grančai; Branislav Horváth
Authors‘ workplace:
Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra farmakognózie a botaniky, Bratislava
1; Univerzita Komenského v Bratislave, Farmaceutická fakulta, Centrálne laboratórium NMR
2
Published in:
Čes. slov. Farm., 2016; 65, 128-131
Category:
Review Articles
*Venované Dr.h.c. prof. RNDr. Václavovi Suchému, DrSc. pri príležitosti jeho životného jubilea.
Overview
The paper deals with the isolation and identification of the constituents of Cornus officinalis Sieb. et Zucc. leaves. There was isolated β-sitosterol from petroleum ether extract, glucose and saccharose from methanolic extract and gallic acid, quercetin and quercetin-3-O-glucoside (isoquercitrin) from aqueous-methanolic extract. Isolates were identified by physico-chemical data, and by comparing with authentic samples and literature data. The compounds I – V were isolated from the leaves of Cornus officinalis Sieb. et Zucc. for the first time.
Key words:
Cornus officinalis Sieb. et Zucc. • Cornaceae • petroleum ether extract • methanolic extract • aqueous-methanolic extract
Sources
1. Xiang Q., Boufford D. E. Cornaceae. Flora of China. 2005; 14, 206–221.
2. Forman V., Haladová M., Grančai D., Ficková M. Antiproliferative activities of water infusions from leaves of five Cornus L. species. Molecules 2015; 20, 22546–22552.
3. Forman V., Bukovský M., Grančai D. Immunomodulatory activity of leaf infusions of selected Cornaceae species on human leukocytes. Nat. Prod. Commun. 2016; 11, 685–687.
4. Miyazawa M., Kameoka H. Volatile flavor components of crude drugs 7. Volatile flavor components of Corni fructus (Cornus officinalis Sieb. et. Zucc.). Agric. Biol. Chem. 1989; 53, 3337–3340.
5. Hatano T., Yasuhara T., Abe R,. Okuda T. Tannins of cornaceous plants 3. A galloylated monoterpene glucoside and a dimeric hydrolyzable tannin from Cornus officinalis. Phytochemistry 1990; 29, 2975–2978.
6. He Y-Q., Ma G-Y., Peng J., Ma Z-Y., Hamann M. T. Liver X receptor and peroxisome proliferator-activated receptor agonist from Cornus alternifolia. Biochim. Biophys. Acta 2012; 1820, 1021–1026.
7. Hatano T., Yasuhara T., Okuda T. Tannins of cornaceous plants 2. Cornusiin-D, cornusiin-E and cornusiin-F, new dimeric and trimeric hydrolyzable tannins from Cornus officinalis. Chem. Pharm. Bull. 1989; 37, 2665–2669.
8. Seeram N. P., Schutzki R., Chandra A., Nair M. G. Characterization, quantification, and bioactivities of anthocyanins in Cornus species. J. Agric. Food Chem. 2002; 50, 2519–2523.
9. Ma Z-Y., Yao B-h., Wang L-j., He Y-Q. Chemical constituents from Cornus officinalis and their biological activity. Chron. Young Scientists 2012; 3, 209–211.
10. Lee S. H., Tanaka T., Nonaka G-I., Nishioka I. Tannins and related compounds 86. Sedoheptulose digallate from Cornus officinalis. Phytochemistry 1989; 28, 3469–3472.
11. Pitra J., Štěrba J. Třídění silikagélu pro chromatografii. Chem. Listy 1963; 57, 389–391.
12. Šaršúnová M., Schwarz V., Michalec Č. Chromatografia na tenkých vrstvách vo farmácii a klinickej biochémii. Bratislava: Osveta 1977.
13. Mabry T. J., Markham K. R., Thomas M. R. The systematic identification of flavonoids, New York: Springer Verlag 1970.
14. Friedrich H. Über das Vorkommen von Isorhamnetin-Glykosiden in den Blüten von Calendula officinalis L. Arch. Farm. 1962; 295, 59–66.
15. Friedrich H. Untersuchungen über die Isorhamnetin-Glykoside aus den Blüten von Calendula officinalis L. Arch. Farm. 1962; 295, 464–471.
16. Suchý V., Grančai D., Grznár K., Tomko J., Dolejš L., Buděšínský M. Non-alkaloidal constituents of Veratrum album subsp. Lobelianum (BERNH.) Suessenguth. Acta Universitatis Palackianae Olomucensis 1980; 93, 141–147.
17. Devon T. K., Scott A. I. Handbook of Naturally Occuring Compounds: Vol. I Acetogenins, Shikimates and Carbohydrates. New York: Academic Press 1975.
18. PUBCHEM database. [online]. [cit. 2016-20-04]. Dostupné na:
http://pubchem.ncbi.nlm.nih.gov
19. Dictionary of Natural Products on CD-ROM, Chapman and Hall, Version 6:2, January 1998.
Labels
Pharmacy Clinical pharmacologyArticle was published in
Czech and Slovak Pharmacy
2016 Issue 4
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