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Year 2022 in review – Anaesthesia


Authors: J. Bláha
Authors‘ workplace: Klinika anesteziologie, resuscitace a intenzivní medicíny, 1. lékařská fakulta Univerzity Karlovy, a Všeobecná fakultní nemocnice v Praze
Published in: Anest. intenziv. Med., 33, 2022, č. 6, s. 264-270
Category: Review Article
doi: https://doi.org/10.36290/aim.2022.041

Overview

By 2022, publishing has already returned to the standard. This means that the global SARS-CoV-2 pandemic for anaesthesiologists is all but forgotten, and the safety of anesthesia is again the dominant issue. However, in addition to the traditional search for answers to whether we should prefer regional or general anesthesia and for which procedures and what is the best prevention of PONV, there is now another associated topic - postoperative delirium and postoperative cognitive dysfunction. Although both entities are crucial to the overall perioperative course, they still need more attention. This is even though, especially in elderly patients, they have already been shown to significantly affect perioperative morbidity and mortality. Moreover, to the surprise of many, recent data show that their incidence is not so much dependent on the type of anesthesia but on the quality of its administration. This text aims to briefly summarize some key publications in the field of anesthesiology and to highlight papers that should not escape attention.

Keywords:

General anesthesia – publications – regional anesthesia – anaesthesiology – 2021 – postoperative delirium – PONV


Sources

1. Cardia L. Remimazolam: an ultrashort‑acting intravenous anesthetic suitable for general anesthesia. Minerva Anestesiol. 2021 Oct;87(10):1059-1063. doi: 10.23736/S0375- 9393. 21. 16006-7. Epub 2021 Aug 2. PMID: 34337928.

2. Kim SH, Fechner J. Remimazolam – current knowledge on a new intravenous benzodiazepine anesthetic agent. Korean J Anesthesiol. 2022 Aug;75(4):307-315. doi: 10.4097/ kja.22297. Epub 2022 May 19. PMID: 35585830; PMCID: PMC9346281.

3. Kim KM. Remimazolam: pharmacological characteristics and clinical applications in anesthesiology. Anesth Pain Med (Seoul). 2022;17(1):1-11. doi: 10.17085/apm.21115. Epub 2022 Jan 20. PMID: 35139608; PMCID: PMC8841266.

4. Chae D, Kim HC, Song Y, Choi YS, Han DW. Pharmacodynamic analysis of intravenous bolus remimazolam for loss of consciousness in patients undergoing general anaesthesia: a randomised, prospective, double‑blind study. Br J Anaesth. 2022;129(1):49-57. doi: 10.1016/j.bja.2022. 02. 040. Epub 2022 May 11. Erratum in: Br J Anaesth. 2022 Nov;129(5):831. PMID: 35562226.

5. Choi JY, Lee HS, Kim JY, Han DW, Yang JY, Kim MJ, et al. Comparison of remimazolam‑based and propofol‑based total intravenous anesthesia on postoperative quality of recovery: A randomized non‑ inferiority trial. J Clin Anesth. 2022;82:110955. doi: 10.1016/j.jclinane. 2022.110955. Epub 2022 Aug 25. PMID: 36029704.

6. Mao Y, Guo J, Yuan J, Zhao E, Yang J. Quality of Recovery After General Anesthesia with Remimazolam in Patients’ Undergoing Urologic Surgery: A Randomized Controlled Trial Comparing Remimazolam with Propofol. Drug Des Devel Ther. 2022;16:1199-1209. doi: 10.2147/DDDT.S359496. PMID: 35509490; PMCID: PMC9058002.

7. Song SW, Jang YN, Yoon MW, Jeon YG. Quality of recovery in patients administered remimazolam versus those administered an inhalant agent for the maintenance of general anesthesia: a randomized control trial. BMC Anesthesiol. 2022;22(1):226. doi: 10.1186/ s12871-022-01770-x. PMID: 35842575; PMCID: PMC9288018.

8. Yi F, Xiao H, Zhu T, Man Y, Ji F. Prevention of postoperative nausea and vomiting after gynaecological day surgery under remimazolam general anesthesia: a randomized double‑blind controlled study. BMC Anesthesiol. 2022;22(1):292. doi: 10.1186/s12871-022-01835-x. PMID: 36109691; PMCID: PMC9476338.

9. Nair A, Seelam S. Ciprofol – a game changing intravenous anesthetic or another experimental drug! Saudi J Anaesth. 2022;16(2):258-259. doi: 10.4103/sja.sja_898_21. Epub 2022 Mar 17. PMID: 35431734; PMCID: PMC9009555.

10. Wang X, Wang X, Liu J, Zuo YX, Zhu QM, Wei XC, et al. Effects of ciprofol for the induction of general anesthesia in patients scheduled for elective surgery compared to propofol: a phase 3, multicenter, randomized, double‑blind, comparative study. Eur Rev Med Pharmacol Sci. 2022;26(5):1607-1617. doi: 10.26355/eurrev_202203_28228. PMID: 35302207.

11. Chen BZ, Yin XY, Jiang LH, Liu JH, Shi YY, Yuan BY. The efficacy and safety of ciprofol use for the induction of general anesthesia in patients undergoing gynecological surgery: a prospective randomized controlled study. BMC Anesthesiol. 2022;22(1):245. doi: 10.1186/ s12871-022-01782-7. PMID: 35922771; PMCID: PMC9347095.

12. Qin K, Qin WY, Ming SP, Ma XF, Du XK. Effect of ciprofol on induction and maintenance of general anesthesia in patients undergoing kidney transplantation. Eur Rev Med Pharmacol Sci. 2022;26(14):5063-5071. doi: 10.26355/eurrev_202207_29292. PMID: 35916802. 1

13. Ding YY, Long YQ, Yang HT, Zhuang K, Ji FH, Peng K. Efficacy and safety of ciprofol for general anaesthesia induction in elderly patients undergoing major noncardiac surgery: A randomised controlled pilot trial. Eur J Anaesthesiol. 2022;39(12):960-963. doi: 10.1097/ EJA.0000000000001759. PMID: 36214498.

14. Teng Y, Ou M, Wang X, Zhang W, Liu X, Liang Y, et al. Efficacy and safety of ciprofol for the sedation/anesthesia in patients undergoing colonoscopy: Phase IIa and IIb multi‑center clinical trials. Eur J Pharm Sci. 2021;164:105904. doi: 10.1016/j.ejps.2021.105904. Epub 2021 Jun 8. PMID: 34116176.

15. Chen X, Guo P, Yang L, Liu Z, Yu D. Comparison and Clinical Value of Ciprofol and Propofol in Intraoperative Adverse Reactions, Operation, Resuscitation, and Satisfaction of Patients under Painless Gastroenteroscopy Anesthesia. Contrast Media Mol Imaging. 2022;2022:9541060. doi: 10.1155/2022/9541060. PMID: 35935320; PMCID: PMC9314164.

16. Li J, Wang X, Liu J, Wang X, Li X, Wang Y, et al. Comparison of ciprofol (HSK3486) versus propofol for the induction of deep sedation during gastroscopy and colonoscopy procedures: A multi‑ centre, non‑ inferiority, randomized, controlled phase 3 clinical trial. Basic Clin Pharmacol Toxicol. 2022;131(2):138-148. doi: 10.1111/bcpt.13761. Epub 2022 Jun 10. PMID: 35653554; PMCID: PMC9543620.

17. Wei A, Yang L, Ma S, Jin G, Yang M, Zhou J. A case report of ciprofol overdose during anesthesia/analgesia and literature review: clinical presentation, blood pressure, and management. J Int Med Res. 2022;50(11):3000605221132466. doi: 10.1177/03000605221132466. PMID: 36366740; PMCID: PMC9659933.

18. Tan C, Yan S, Shen J, Wu H, Yu L, Wang Y, et al. Effects of dexmedetomidine on cardiac electrophysiology in patients undergoing general anesthesia during perioperative period: a randomized controlled trial. BMC Anesthesiol. 2022;22(1):271. doi: 10.1186/s12871- 022-01811-5. PMID: 36008759; PMCID: PMC9404616.

19. Guo L, Liu Y, Wang M. Effect of Perioperative Dexmedetomidine Anesthesia on Prognosis of Elderly Patients with Gastrointestinal Tumor Surgery. Comput Math Methods Med. 2022 Jul 21;2022:7889372. doi: 10.1155/2022/7889372. PMID: 35912157; PMCID: PMC9334077.

20. Behera BK, Misra S, Jena SS, Mohanty CR. The effect of perioperative dexmedetomidine on postoperative bowel function recovery in adult patients receiving general anesthesia. Minerva Anestesiol. 2022;88(1-2):51-61. doi: 10.23736/S0375-9393. 21. 15773-6. Epub 2021 Sep 16. PMID: 34527407.

21. Mohsin S, Ahmad Ganaie Z, Kundi H, Ahmed MB, Riaz B, Khurshid Ahmed N, et al. Comparison of Fentanyl and Dexmedetomidine in Preventing an Increase in Heart Rate During Intubation Among Patients Undergoing General Anesthesia: A Meta‑Analysis. Cureus. 2022;14(6):e26194. doi: 10.7759/cureus.26194. PMID: 35891845; PMCID: PMC9306395.

22. Fonseca FJ, Ferreira L, Rouxinol‑Dias AL, Mourão J. Effects of dexmedetomidine in non‑operating room anesthesia in adults: a systematic review with meta‑analysis. Braz J Anesthesiol. 2021 Dec 20:S0104-0014(21)00420-6. doi: 10.1016/j.bjane.2021. 12. 002. Epub ahead of print. PMID: 34933035.

23. Zhou W, Wang J, Yang D, Tian S, Tan C, Yang Y, et al. Effects of dexmedetomidine on glucose‑related hormones and lactate in non‑diabetic patients under general anesthesia: a randomized controlled trial. Minerva Anestesiol. 2022;88(1-2):8-15. doi: 10.23736/S0375- 9393. 21. 15734-7. Epub 2021 Oct 28. PMID: 34709010.

24. Sin JCK, Tabah A, Campher MJJ, Laupland KB, Eley VA. The Effect of Dexmedetomidine on Postanesthesia Care Unit Discharge and Recovery: A Systematic Review and Meta‑Analysis. Anesth Analg. 2022;134(6):1229-1244. doi: 10.1213/ANE.0000000000005843. Epub 2022 Jan 27. PMID: 35085107.

25. Khanna SS, Mohammed Abdul MS, Fatima U, Garlapati H, Qayyum MA, Gulia SK. Role of general anesthetic agents in postoperative nausea and vomiting: A review of literature. Natl J Maxillofac Surg. 2022;13(2):190-194. doi: 10.4103/njms.NJMS_146_20. Epub 2022 Jun 15. PMID: 36051800; PMCID: PMC9426712.

26. Toleska M, Shosholcheva M, Dimitrovski A, Kartalov A, Kuzmanovska B, Dimitrovska NT. Is Multimodal Anesthesia Effecting Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy? Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2022;43(2):51-58. doi: 10.2478/prilozi-2022-0018. PMID: 35843914.

27. Massoth C, Schwellenbach J, Saadat‑Gilani K, Weiss R, Pöpping D, Küllmar M, et al. Impact of opioid‑free anaesthesia on postoperative nausea, vomiting and pain after gynaecological laparoscopy – A randomised controlled trial. J Clin Anesth. 2021;75:110437. doi: 10.1016/j.jclinane.2021.110437. Epub 2021 Jul 3. PMID: 34229292.

28. Bhakta P, Karim HMR, O’Brien B, Mugawar M. Comment on: „Impact of opioid‑free anaesthesia on postoperative nausea, vomiting and pain after gynaecological laparoscopy - A randomised controlled trial“. J Clin Anesth. 2021;75:110492. doi: 10.1016/j.jclinane. 2021.110492. Epub 2021 Aug 27. PMID: 34461374.

29. Ahmed MM, Tian C, Lu J, Lee Y. Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Analgesia and Nausea and Vomiting After Bariatric Surgery: A Systematic Review and Meta‑Analysis. Asian J Anesthesiol. 2021;59(4):135-151. doi: 10.6859/ aja.202112_59(4).0002. Epub 2021 Nov 19. PMID: 34856740.

30. Wang TT, Lu HF, Poon YY, Wu SC, Hou SY, Chiang MH, et al. Sevoflurane versus desflurane for early postoperative vomiting after general anesthesia in hospitalized adults: A systematic review and meta‑analysis of randomized controlled trials. J Clin Anesth. 2021;75:110464. doi: 10.1016/j.jclinane.2021.110464. Epub 2021 Jul 24. PMID: 34311245.

31. Kienbaum P, Schaefer MS, Weibel S, Schlesinger T, Meybohm P, Eberhart LH, et al. Update PONV – Was gibt es Neues bei der Prophylaxe und Therapie von postoperativer Übelkeit und postoperativem Erbrechen? : Zusammenfassung rezenter Konsensusempfehlungen sowie Cochrane‑Reviews zu Prophylaxe und Therapie postoperativer Übelkeit und postoperativen Erbrechens [Update on PONV‑What is new in prophylaxis and treatment of postoperative nausea and vomiting? : Summary of recent consensus recommendations and Cochrane reviews on prophylaxis and treatment of postoperative nausea and vomiting]. Anaesthesist. 2022;71(2):123-128. German. doi: 10.1007/s00101-021-01045-z. Epub 2021 Oct 1. PMID: 34596699.

32. Mufarrih SH, Qureshi NQ, Yunus RA, Katsiampoura A, Quraishi I, Sharkey A, et al. A systematic review and meta‑analysis of general versus regional anesthesia for lower extremity amputation. J Vasc Surg. 2022 Oct 13:S0741-5214(22)02338-2. doi: 10.1016/j.jvs.2022. 10. 005. Epub ahead of print. PMID: 36243265.

33. Baratta JL, Schwenk ES. Regional versus general anesthesia for ambulatory total hip and knee arthroplasty. Curr Opin Anaesthesiol. 2022 Oct 1;35(5):621-625. doi: 10.1097/ ACO.0000000000001170. Epub 2022 Jul 27. PMID: 35900744.

34. Gerner P, Cozowicz C, Memtsoudis SG. Outcomes After Orthopedic Trauma Surgery - What is the Role of the Anesthesia Choice? Anesthesiol Clin. 2022;40(3):433-444. doi: 10.1016/j.anclin.2022. 04. 001. Epub 2022 Jul 12. PMID: 36049872.

35. Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, et al; REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) Investigators. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial. Ann Intern Med. 2022;175(7):952-960. doi: 10.7326/M22-0320. Epub 2022 Jun 14. PMID: 35696684.

36. Thepsoparn M, Punyawattanakit P, Jaruwangsanti N, Singhatanadgige W, Chalermkitpanit P. Effects of general anesthesia with and without thoracic epidural block on length of stay after open spine surgery: a single‑blinded randomized controlled trial. Spine J. 2022;22(10):1694-1699. doi: 10.1016/j.spinee.2022. 05. 015. Epub 2022 Jun 6. PMID: 35671941.

37. Shui M, Zhao D, Xue Z, Wu A. Impact of Spinal/Epidural Anesthesia Versus General Anesthesia on Perioperative Outcomes in Patients Undergoing Lumbar Spine Surgery: An Updated Systematic Review and Meta‑analysis. Clin Spine Surg. 2022 Aug 4. doi: 10.1097/BSD.0000000000001374. Epub ahead of print. PMID: 35943881.

38. Liu HY, Yang LL, Dai XY, Li ZP. Local anesthesia with sedation and general anesthesia for the treatment of chronic subdural hematoma: a systematic review and meta‑analysis. Eur Rev Med Pharmacol Sci. 2022;26(5):1625-1631. doi: 10.26355/eurrev_202203_28230. PMID: 35302209.

39. Lei J, Pu H, Wu Z, Huang Q, Yang X, Liu G, et al. Local versus general anesthesia for endovascular aneurysm repair in ruptured abdominal aortic aneurysm: A systematic review and meta‑analysis. Catheter Cardiovasc Interv. 2022;100(4):679-686. doi: 10.1002/ ccd.30326. Epub 2022 Jul 8. PMID: 35801490.

40. Ahmad F, Ali L, Ahmed M, Yasrab M, Khusdil A; Samiullah. Thoracic Epidural Versus General Anaesthesia For Laparoscopic Cholecystectomy: A Randomized Controlled Trial. J Ayub Med Coll Abbottabad. 2022;34(2):279-282. doi: 10.55519/JAMC-02- 9071. PMID: 35576286.

41. Della Corte L, Mercorio A, Morra I, Riemma G, De Franciscis P, Palumbo M, et al. Spinal Anesthesia versus General Anesthesia in Gynecological Laparoscopic Surgery: A Systematic Review and Meta‑Analysis. Gynecol Obstet Invest. 2022;87(1):1-11. doi: 10.1159/000521364. Epub 2021 Dec 16. PMID: 34915508.

42. Duan M, Chen Y, Sun L. Outcomes of Retrograde Intrarenal Surgery Performed Under Neuraxial vs. General Anesthesia: An Updated Systematic Review and Meta‑Analysis. Front Surg. 2022;9:853875. doi: 10.3389/fsurg.2022.853875. PMID: 35360428; PMCID: PMC8960175.

43. Janjua MS, Spurling BC, Arthur ME. Postoperative Delirium. In: StatPearls. edn. Treasure Island (FL): StatPearls Publishing; 2022.

44. Li T, Li J, Yuan L, Wu J, Jiang C, Daniels J, et al; RAGA Study Investigators. Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial. JAMA. 2022 Jan 4;327(1):50-58. doi: 10.1001/jama.2021.22647. Erratum in: JAMA. 2022;327(12):1188. PMID: 34928310; PMCID: PMC8689436.

45. Zhu X, Yang M, Mu J, Wang Z, Zhang L, Wang H, et al. The Effect of General Anesthesia vs. Regional Anesthesia on Postoperative Delirium‑A Systematic Review and Meta‑Analysis. Front Med (Lausanne). 2022;9:844371. doi: 10.3389/fmed.2022.844371. PMID: 35419373; PMCID: PMC8995788.

46. Bhushan S, Huang X, Duan Y, Xiao Z. The impact of regional versus general anesthesia on postoperative neurocognitive outcomes in elderly patients undergoing hip fracture surgery: A systematic review and meta‑analysis. Int J Surg. 2022;105:106854. doi: 10.1016/j. ijsu.2022.106854. Epub 2022 Aug 27. PMID: 36031067.

47. Li T, Dong T, Cui Y, Meng X, Dai Z. Effect of regional anesthesia on the postoperative delirium: A systematic review and meta‑analysis of randomized controlled trials. Front Surg. 2022;9:937293. doi: 10.3389/fsurg.2022.937293. PMID: 35959124; PMCID: PMC9360531.

48. Wei W, Zheng X, Gu Y, Fu W, Tang C, Yao Y. Effect of general anesthesia with thoracic paravertebral block on postoperative delirium in elderly patients undergoing thoracoscopic lobectomy: a randomized‑ controlled trial. BMC Anesthesiol. 2022;22(1):1. doi: 10.1186/ s12871-021-01532-1. PMID: 34979943; PMCID: PMC8722018.

49. Pérez‑Otal B, Aragón‑Benedí C, Pascual‑Bellosta A, Ortega‑Lucea S, Martínez‑Ubieto J, Ramírez‑Rodríguez JM; Research Group in Anaesthesia, Resuscitation, and Perioperative Medicine of Institute for Health Research Aragón (ISS Aragón). Neuromonitoring depth of anesthesia and its association with postoperative delirium. Sci Rep. 2022;12(1):12703. doi: 10.1038/s41598-022-16466-y. PMID: 35882875; PMCID: PMC9325758.

50. Ma D, Ma J, Chen H, Mu D, Kong H, Yu L. Nociception monitors vs. standard practice for titration of opioid administration in general anesthesia: A meta‑analysis of randomized controlled trials. Front Med (Lausanne). 2022;9:963185. doi: 10.3389/fmed.2022.963185. PMID: 36091708; PMCID: PMC9454957.

51. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, et al; Nomenclature Consensus Working Group. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Br J Anaesth. 2018;121(5):1005-1012. doi: 10.1016/j.bja.2017. 11. 087. Epub 2018 Jun 15. PMID: 30336844; PMCID: PMC7069032.

52. Negrini D, Wu A, Oba A, Harnke B, Ciancio N, Krause M, et al. Incidence of Postoperative Cognitive Dysfunction Following Inhalational vs Total Intravenous General Anesthesia: A Systematic Review and Meta‑Analysis. Neuropsychiatr Dis Treat. 2022;18:1455-1467. doi: 10.2147/NDT.S374416. PMID: 35874550; PMCID: PMC9296882.

53. Grabert J, Coburn M. Ist das Delir unabhängig vom Anästhesieverfahren? Was uns REGAIN und RAGA lehren [Is delirium independent from the anesthesia technique?-What REGAIN and RAGA teach us]. Anaesthesist. 2022;71(5):400-402. German. doi: 10.1007/s00101- 022-01104-z. Epub 2022 Feb 23. PMID: 35199183; PMCID: PMC9068640.

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Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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