-
Medical journals
- Career
Medical News
Osimertinib in the Treatment of Patients with NSCLC with Secondary EGFR T790M Mutation – Case Study
10. 6. 2020 Source: Lung CancerNon-small cell lung cancer (NSCLC) is a genetically heterogeneous disease. Individualization of therapy based on the presence of specific tumor cell mutations is therefore crucial for choosing the optimal therapy for these patients. One of the targeted treatment options for patients with NSCLC with an activating mutation in the epidermal growth factor receptor (EGFR) gene is osimertinib, a third-generation EGFR tyrosine kinase inhibitor (EGFR TKI). We present a case study of a patient with NSCLC treated with osimertinib after disease…
Chronic Thromboembolic Pulmonary Hypertension – Overview of Pathophysiology, Diagnosis, and Treatment
Chronic thromboembolic pulmonary hypertension (CTEPH) is defined by the 2015 ESC/ERS guidelines as symptomatic pulmonary hypertension with persistent defects in lung perfusion despite adequate…9. 6. 2020 Source: Pulmonary hypertension (CTEPH, PAH)
Effect of Cataract Surgery on Melatonin Secretion in Adults Aged 60 and Over
A study by ophthalmologists and epidemiologists from Nara University in Japan, recently published in JAMA Ophthalmology, examined the relationship between cataract surgery, the use of clear and…8. 6. 2020 Source: Glaucoma
Morning Myopic Shift and Glare in Patients with Advanced Fuchs Endothelial Corneal Dystrophy
A newly published study by a German team analyzes the morning and afternoon differences in various parameters in patients with Fuchs endothelial corneal dystrophy to determine which of them…8. 6. 2020 Source: Glaucoma
Venetoclax in the Treatment of CLL: Open Doors for the Longest Possible Maintenance of Remission Without Active Therapy
William G. Wierda from MD Anderson Cancer Center in Houston, USA, and Francesco P. Tambaro from Azienda Ospedaliera di Rilievo Nazionale Santobono-Pausilipon in Naples, Italy, evaluate in their…8. 6. 2020 Source: Chronic Lymphocytic Leukemia
Temporary Interruption of Treatment or Dose Modification of Ibrutinib in CLL Patients
A team from the Mayo Clinic in Rochester, USA, published a study this March in the journal Cancer Medicine, focusing on aspects of ibrutinib therapy in real clinical practice. The authors evaluated…8. 6. 2020 Source: Chronic Lymphocytic Leukemia
Valproate and Lithium in Maintenance Therapy of Bipolar Affective Disorder
Among the so-called mood stabilizers, drugs commonly used in the therapy of bipolar affective disorder, are valproate and lithium. Canadian authors recently conducted a post hoc analysis of a study…8. 6. 2020 Source: Bipolar Disorder
Anticonvulsants Are Associated with the Least Impact on Sexual Function in Bipolar Disorder Treatment
It is known that in patients with bipolar disorder, in addition to the illness itself, sexual dysfunction is adversely affected by psychotropic medications. A study by Spanish authors recently…8. 6. 2020 Source: Bipolar Disorder
Study PLATON: romiplostim in patients with ITP in real clinical practice
Recently, the results of the PLATON study with romiplostim, which was conducted in Central and Eastern European countries including the Czech Republic, were published. It was an observational…8. 6. 2020 Source: Immune Thrombocytopenia
Pediatric Immune Thrombocytopenia Does Not Overlap with Adult ITP
Immune thrombocytopenia (ITP) is a highly heterogeneous disease characterized by various bleeding manifestations and different needs for treatment or likelihood of remission. The difference is…8. 6. 2020 Source: Immune Thrombocytopenia
Thyroid Disorder Screening in Pregnancy to Be Tested by Pilot Program Starting September
The expectations surrounding the trial launch of the screening program were discussed by Professor Michal Kršek, Chairman of the Czech Endocrinological Society ČLS JEP, on the occasion of the 12th…8. 6. 2020 Source: Thyroid Disorders
How to Communicate and Receive an Oncological Diagnosis
Communicating the truth to a patient about their health condition does not have a very long tradition in the Czech Republic. The Czech healthcare system started emphasizing this aspect, i.e., honest and...4. 6. 2020 Source: Ovarian and Breast Cancer
How to Communicate and Receive an Oncological Diagnosis
Communicating the truth about a patient's health condition does not have a very long tradition in the Czech Republic. The Czech healthcare system only began to emphasize this aspect, that is, honest and...4. 6. 2020 Source: Lung Cancer
Multiparametric Magnetic Resonance in Predicting Progression of Low-Risk Prostate Cancer
A newly published study has demonstrated the utility of imaging using multiparametric magnetic resonance imaging (mpMRI) and its interpretation using PI-RADS version 2 (Prostate Imaging Reporting and…4. 6. 2020 Source: Prostate Health Index
Magnetic Resonance Can Reduce the Need for Prostate Biopsies
As early as 2013, Czech experts demonstrated that in patients with elevated prostate-specific antigen (PSA) levels, imaging using a 3-Tesla magnetic resonance (3T MRI) can replace biopsy in many…4. 6. 2020 Source: Prostate Health IndexLogin#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
- Career