Medical News

When the Cause of Hematomas in Anticoagulated Patients is Not Anticoagulants –⁠ Case Report

18. 11. 2022 Source: Acquired Hemophilia

Not every bleeding during anticoagulation, especially if within the therapeutic range, can be attributed to this treatment. Particularly in older individuals and the presence of typical extensive hematomas, it is necessary to consider another cause, such as acquired hemophilia A. The following case report illustrates how such a case can be detected and what can be done to improve the patient's prognosis.

Rebound effect after denosumab discontinuation in a patient with lung cancer

The case study of a patient with metastatic lung cancer describes the emergence of vertebral fractures following the discontinuation of denosumab. This antiresorptive treatment was halted…

16. 11. 2022 Source: Prevention of Bone Events

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Prevention of Symptomatic Skeletal Events in Postmenopausal Women with Advanced ER-Positive Breast Cancer

Advanced breast cancer with the presence of estrogen receptors is one of the most common cancers worldwide. Hormonal treatment for this malignancy is highly effective, but it is accompanied by risks…

16. 11. 2022 Source: Prevention of Bone Events

Current Approaches to COPD Therapy According to GOLD Recommendations and in the Conditions of Czech Practice

Chronic Obstructive Pulmonary Disease (COPD) represents a significant global cause of morbidity and mortality with a high prevalence that is expected to increase significantly in the coming years.…

15. 11. 2022 Source: Treatment of Asthma and COPD

Impact of Rehabilitation on the Health of Patients with COPD

According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD), pulmonary rehabilitation is one of the most effective therapeutic interventions for reducing dyspnea, improving…

15. 11. 2022 Source: Treatment of Asthma and COPD

ESC 2022: Heart Failure with Preserved Ejection Fraction as an Underdiagnosed Problem: How to Increase Its Detection in Everyday Practice?

During this year's European Society of Cardiology Congress (ESC 2022), alarming information was shared, indicating that heart failure with preserved ejection fraction of the left ventricle (HFpEF) is…

14. 11. 2022 Source: Heart Failure

Estimated Worldwide Prevalence of Population with AAT Deficiency with MZ Alleles

Alpha-1-antitrypsin deficiency (AATD) with the MZ genotype was until recently associated with negligible or low risk for lung and liver tissue damage. However, growing evidence suggests that carriers…

14. 11. 2022 Source: Deficiency of Alpha-1-Antitrypsin

Persistent Symptom Control with s.c. Supplementation of C1 Inhibitor in Prophylactic Treatment of HAE

The open-label extension of the COMPACT study with subcutaneous C1 inhibitor in the prophylaxis of hereditary angioedema (HAE) has brought fresh results, shedding light on the treatment's impact on…

14. 11. 2022 Source: Hereditary Angioedema

Inhibitor of Activated Factor XII Garadacimab in Prophylaxis of HAE Attacks

Hereditary angioedema (HAE) is an autosomal dominant inherited disease characterized by a deficiency of C1 inhibitor. This condition leads to excessive production of bradykinin, which is responsible…

14. 11. 2022 Source: Hereditary Angioedema

Good news for sleep in patients with axial spondyloarthritis –⁠ ixekizumab effectively reduces night-time back pain

The targeted treatment of axial spondyloarthritis currently relies on the anti-inflammatory effects of tumor necrosis factor (TNF) inhibitors, interleukin IL-17 inhibitors, and Janus kinase (JAK)…

14. 11. 2022 Source: Biological Treatment

Two Current Perspectives on the Importance of (Par)enteral Nutrition in Cancer Patients

Adequate (par)enteral nutrition is crucial for cancer patients in terms of prognosis and quality of life. The following recent studies examined parenteral nutrition as an alternative to ileostomy in…

14. 11. 2022 Source: Parenteral Nutrition

To what extent can improvement of nutritional status through parenteral nutrition affect the results of oncological treatment?

Just like cancer patients and their caregivers, doctors often overlook the risk of malnutrition. Good nutrition can be a predictor of survival in patients with malignancies.

14. 11. 2022 Source: Parenteral Nutrition

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