Medical News

How to Choose the Ideal Venotonic or Vasoprotective –⁠ Which Properties Are Key?

11. 2. 2020 Source: Venous Insufficiency

Medicines and dietary supplements containing flavonoids, often hesperidin or diosmin, are available on the market. What should you consider when choosing these products?

The Role of Probiotics in the Prevention of Childhood Infections

Although common acute respiratory and gastrointestinal infections are a part of childhood, they pose a significant burden on families and the healthcare and social care system. An unexpected role in…

11. 2. 2020 Source: GI, colic and microbiome

Does Emicizumab Change Routine Clinical Practice?

With the increasing number of patients with hemophilia A being treated with emicizumab, the question arises whether its use in any way changes established clinical practice. A team of American…

11. 2. 2020 Source: Quality Life Even with Hemophilia

Should We Test for Alpha-1-Antitrypsin in All COPD Patients?

Approximately 1–2% of patients with chronic obstructive pulmonary disease (COPD) have an alpha-1-antitrypsin (AAT) deficiency. This is an underdiagnosed genetic disorder that leads to rapid…

10. 2. 2020 Source: Deficiency of Alpha-1-Antitrypsin

Lorlatinib as an Alternative to CNS Radiotherapy in Patients with NSCLC −⁠ Case Studies

Two remarkable case studies from authors at the Netherlands Cancer Institute Antoni van Leeuwenhoek in Amsterdam present patients with advanced NSCLC with metastatic CNS involvement. Treatment with…

10. 2. 2020 Source: Genetic Profile and Treatment of NSCLC

Idarucizumab reverses the anticoagulant effect of dabigatran even in patients with impaired renal function –⁠ clinical practice commentary

Along with the results of a subanalysis of the RE-VERSE AD study, which demonstrated the efficacy of idarucizumab in reversing the anticoagulant effect of dabigatran regardless of the level of renal…

10. 2. 2020 Source: Anticoagulant Treatment

Does The Use of Levothyroxine in Women with Thyroid Peroxidase Antibodies Affect The Risk of Miscarriage and Premature Birth?

Women with thyroid peroxidase antibodies have a higher risk of miscarriage and premature birth, even if they have normal thyroid function. The British study presented below aimed to clarify whether…

10. 2. 2020 Source: Thyroid Disorders

Comparison of Clinical Outcomes of TKA Implantation: ATTUNE vs. SIGMA

The ATTUNE total knee arthroplasty (TKA) system was introduced to the market in 2013 as a successor to the popular SIGMA system. The new type of knee endoprosthesis is designed to provide better…

7. 2. 2020 Source: Large Joints

Clinical Benefit of Mucolytics in the Treatment of Upper Respiratory Tract Infections

A new review based on published controlled and observational studies as well as real-world practice experiences demonstrates the benefits of ambroxol, bromhexine, carbocisteine, erdosteine,…

6. 2. 2020 Source: Cough Therapy

Prevalence and Incidence of Age-Related Macular Degeneration in Europe –⁠ Current Overview and Trend Analysis

A comprehensive review article by authors from Bonn, Germany, published late last year in the British Journal of Ophthalmology, provides current data and estimates of the incidence and prevalence of…

6. 2. 2020 Source: Glaucoma

Changes in Intestinal Microflora Correlate with Disease Activity in Patients with Lupus Erythematosus

The role of intestinal microflora in the pathogenesis of autoimmune diseases, including lupus erythematosus, has been discussed for a long time. An American study discovered a specific bacterium…

4. 2. 2020 Source: Arthritis

Risk Factors and Therapy of Chronic Leg Ulcers Lasting More Than 6 Months

The therapy of chronic leg ulcers in diabetics continues to be a significant challenge for attending physicians and surgeons. Authors of a recently published study have addressed the risk factors, clinical...

3. 2. 2020 Source: Wound Healing

LDL cholesterol: a new risk factor for the onset of venous thromboembolic disease?

Not only do atherosclerotic plaques in the arteries and the risk of heart attack decrease along with LDL cholesterol levels. Results from a large molecular genetic study suggest that lowering its…

3. 2. 2020 Source: Cardiovascular Risks

Polatuzumab Vedotin in Combination Treatment of Patients with R/R DLBCL

Polatuzumab Vedotin is a conjugate of a cytostatic agent and an antibody against CD79b, a component of the B-lymphocyte receptor typically expressed by diffuse large B-cell lymphoma (DLBCL) cells. In…

3. 2. 2020 Source: Non-Hodgkin Lymphomas and CLL

zhodnocení výsledků vyšetření u lékaře 2356x1571

End of Unnecessary Biopsies? Prostate Health Index (PHI) in Detecting Aggressive Carcinoma

The Prostate Health Index (PHI) combines the results of three blood-derived parameters: total PSA (tPSA), free PSA (fPSA), and [-2]proPSA (p2PSA) into a single numerical score: PHI = (p2PSA / fPSA ×…

2. 2. 2020 Source: Prostate Health Index

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