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News Minimally Invasive Treatment of Pilonidal Sinus: Laser and Negative Pressure Therapy as a Gentle and Effective Modality

The increasing incidence of pilonidal sinus contributes to the development of new treatment methods. Experiences from AGEL Hospital Přerov show that the methods SiLaC (sinus laser ablation of the cyst) and NPWT (negative pressure wound therapy) represent a gentle and effective approach for pilonidal sinus, accelerating treatment and subsequent recovery.

Source: Wound Healing 24. 11. 2023

News Prof. Petr Marusič: Is the Success of Therapy Changing with the Arrival of New Antiepileptics?

At the XXV. postgraduate course in epileptology, 'Jiří Dolanský Days', prof. MUDr. Petr Marusič, Ph.D., from the Neurological Clinic of the 2nd Faculty of Medicine, Charles University, and Motol University Hospital, lectured on the topic of changes in the efficacy of epilepsy treatment with the arrival of new anti-seizure medications.

Source: Epilepsy 2. 12. 2022

Články časopisu

Author of the article: Petr Klement, Jan Hřídel Source: Časopis lékařů českých | 3/2018 27. 6. 2018

News Low-Molecular-Weight Heparins in Thromboprophylaxis After Major Orthopedic and Traumatological Procedures According to Current Recommendations

Patients after major orthopedic and traumatological procedures are at high risk of thromboembolic disease. This is especially true for people undergoing hip and knee replacement or patients with a proximal femur fracture and severe lower limb injury. The routine implementation of pharmacological thromboprophylaxis, such as low-molecular-weight heparins, is currently the gold standard in perioperative care in these cases.

Source: Thromboprophylaxis 20. 6. 2022

News Inosine pranobex in the treatment of influenza and other respiratory infections of viral etiology

The antiviral inosine pranobex is a clinically proven immunomodulator for the treatment of patients from 1 year of age, indicated for a wide range of diseases with manifestations of immune insufficiency and viral infections. It acts by a direct antiviral effect, modulates the immune system, and also finds application in the treatment of acute viral respiratory diseases, such as influenza and other seasonal viral infections.

Source: Viral infections 24. 2. 2022

News With Prof. Pavel Žák about Current Trends and Future Perspectives in Bone Marrow Transplantation and the Role of Carmustine in this Context

Hematopoietic stem cell transplantation has an indispensable place in the treatment of hemato-oncological diseases. We discuss current trends in this area, the significance and benefits of carmustine, the choice between BEAM and TEAM regimens, and the future of bone marrow transplantation in the context of new technologies with the head of the 4th Department of Hematology of the Faculty of Medicine, Charles University and University Hospital Hradec Králové, Prof. MUDr. Pavel Žák, Ph.D.

Source: Oncological Treatment 10. 6. 2024

News Fixed Combination of Candesartan/Amlodipine in the Treatment of Arterial Hypertension

Arterial hypertension is a significant cardiovascular risk factor. A variety of antihypertensives are used in therapy, both in monotherapy and combination treatment. Often, it is necessary to treat patients with a combination of multiple antihypertensives to achieve satisfactory blood pressure values. A popular fixed combination with a favorable pharmacodynamic and pharmacokinetic profile is the combination of candesartan and amlodipine, whose effects have been verified by numerous extensive clinical studies.

Source: Sartans in the Treatment of Hypertension 19. 1. 2021

News Combination of Arterial Hypertension and Increased Heart Rate as a Significant Cardiovascular Risk Factor

Heart rate is one of the basic vital signs that should be regularly measured. Sinus tachycardia can be physiological under certain conditions. However, a patient with resting tachycardia should always be examined, as tachycardia can be a symptom of a serious health problem. Especially in patients with arterial hypertension, a rapid heart rate significantly increases cardiovascular risk.

Source: Cardiovascular Continuum 23. 11. 2020

News Effectiveness of the Sonicare For Kids Toothbrush in Preschool Children

A comparative study conducted as part of a graduation thesis in the field of Certified Dental Hygienist offers a comparison of the cleaning effectiveness of a manual toothbrush and a sonic toothbrush in children aged 4−5.5 years. The sonic toothbrush proved to be an effective tool with good results for this age group.

Source: Dental Care 15. 10. 2023

News Levothyroxine and the Interchangeability of Preparations Containing It

Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women. Levothyroxine is a drug with a narrow therapeutic window, and its bioavailability is influenced by many factors, including consumed foods, medications, and beverages.

Source: Thyroid Disorders 6. 11. 2020

News Prostate Health Index and its Possible Use in Clinical Practice

With the increasing incidence of prostate cancer, the effort to improve its diagnostics is also growing. The exclusively used and practice-proven prostate-specific antigen (PSA) continues to play an indispensable role in identifying at-risk patients, but some of its isoforms can also provide important information for deciding the patient's further fate. Based on their combination, a so-called prostate health index (PHI) can be determined. A recently published work by Czech authors assessed the usability of PHI as a parameter suitable for evaluating the aggressiveness of prostate cancer (PC) within the PHIMOPLUKTHOM study.

Source: Prostate Health Index 9. 11. 2020

News Effectiveness of Arginine in Tooth Cleaning Proven (Not Only) by Quantitative Light-Induced Fluorescence

There is no doubt about the benefits of toothpaste in daily dental care. Today, there are numerous studies proving that brushing without toothpaste does not have the same effectiveness as brushing with toothpaste. It is more effective and, thanks to active ingredients, can slow down or even reverse the development of tooth decay.

Source: Dental Caries 4. 5. 2020

News Maintenance Therapy of a Female Patient with AML After Intense Chemotherapy –⁠ Case Study

The following case study presents the case of a female patient with acute myeloid leukemia (AML) who experienced life-threatening complications after the second consolidation chemotherapy, rendering her incapable of undergoing further intense therapy or allogeneic HSCT. In this situation, maintenance therapy with oral azacitidine proved beneficial –⁠ this modality, due to its good tolerance, can be used as a bridge until allo-HSCT can be performed in patients in poor clinical condition.

Source: Acute Myeloid Leukemia 10. 5. 2024

News Pregabalin in the Hands of a General Practitioner

A recent Cochrane systematic review by authors from Oxford University examined the effect of pregabalin in the treatment of postherpetic neuralgia and diabetic neuropathy –⁠ conditions that general practitioners frequently encounter in their practice. Is pregabalin a suitable choice in these indications?

Source: Neuropathic Pain 18. 2. 2020

News Incontinence Dermatitis -⁠ Common, Yet Often Overlooked Diagnosis

Incontinence dermatitis is an inflammatory skin reaction with a prevalence between 3 and 25%, caused by prolonged skin contact with urine or feces. It is classified among contact irritant dermatitis. It causes significant discomfort to patients and can also require difficult and prolonged treatment.

Source: Incontinence 21. 4. 2020