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Články časopisu Primary immunodeficiencies in adults

Author of the article: Jiří Litzman Source: Vnitřní lékařství | 2/2019 15. 3. 2019

News Memantine and Donepezil –⁠ Unity is Strength

Memantine and donepezil are both used in the therapy of Alzheimer's disease (AD). However, how does the combination of these drugs fare in the treatment of moderate to severe AD?

Source: Cognitive in the treatment of Alzheimer's disease 12. 10. 2020

News Hybrid Cooperating Complexes in Osteoarthritis Treatment

Intra-articular application of corticosteroids and hyaluronic acid is part of the treatment of osteoarthritis (OA) in patients for whom oral or topical treatment does not provide sufficient response. The following text addresses the lubricating and protective properties of synovial fluid and the associated choice of suitable intra-articular viscosupplementation, with an emphasis on innovative molecules with high concentrations of hyaluronic acid and low viscosity.

Source: Pain Management 21. 6. 2024

Články časopisu Sexual Dysfunction and its Incidence in Patients with Epilepsy

Author of the article: R. Mařák, M. Pohanka, K. Langová, J. Zapletalová, R. Herzig, P. Kaňovský Source: Česká a slovenská neurologie a neurochirurgie | 3/2010 24. 6. 2010

Články časopisu Case report of a gigantic recurrent angiomyolipoma in a horseshoe kidney

Author of the article: Markéta Hulová, Michal Staník, Daniel Macík, Jan Doležel Source: Česká urologie | 1/2020 9. 3. 2020

Články časopisu Preinvasive Lesions in Gynaecology –⁠ Endometrium

Author of the article: R. Feranec, L. Mouková, Josef Chovanec Source: Klinická onkologie | Supplementum/2013 9. 12. 2013

News Association of M2 Haplotype of the Annexin A5 Gene with Recurrent Reproductive Losses

Annexin A5 (ANXA5) is a placental anticoagulant protein that ensures adequate blood supply to the fetus during pregnancy, and its deficiency can increase the incidence of vascular thrombosis in the placenta. Current research shows that the M2 haplotype of the ANXA5 gene may be associated with recurrent reproductive losses and obstetric complications due to placental disorders.

Source: Genetics 5. 5. 2023

News Sjögren's Syndrome as a Cause of Dry Eye Syndrome

Primary Sjögren's syndrome represents a complex autoimmune disease primarily affecting glands with exocrine secretion. Dry eye syndrome ranks among the most common difficulties for patients with Sjögren's syndrome. Essential pillars of therapy include regular application of preservative-free artificial tears, escalated to anti-inflammatory treatment if necessary.

Source: Ophthalmologic Diseases 2. 5. 2023

News Reduction of Enthesitis in Patients with Psoriatic Arthritis Taking Tofacitinib

Inflammation in the area where a tendon, ligament, or joint capsule attaches to the bone occurs in 35–50% of patients with psoriatic arthritis (PsA). Its presence is associated with higher activity of PsA, and its intensity correlates with the degree of joint damage. Patients with enthesitis are generally in worse functional status and report greater fatigue, pain, and decreased productivity. How can treatment with tofacitinib affect this important domain of PsA?

Source: Arthritis 24. 11. 2023

News Levodropropizine vs. dextromethorphan: Which one to recommend to your patients and why?

Reducing cough intensity and nighttime awakenings, rapid onset of action, simple dosing regimen, and good treatment tolerance—these are the properties we expect from antitussive drugs, not only in pediatrics. So which of these wins in these parameters compared to other commonly used over-the-counter antitussives?

Source: Cough Therapy 12. 11. 2020

Články časopisu Type 2 diabetes mellitus in old age

Author of the article: MUDr. Martina Lášticová Source: Geriatrie a Gerontologie | 2/2014 26. 6. 2014

News Prophylaxis with Enoxaparin After Total Knee or Hip Replacement

Venous thromboembolic disease is a significant cause of complications in surgical patients during and after hospitalization. The authors of a recently published Portuguese observational study evaluated the incidence of complications with prophylaxis using low-molecular-weight heparin (LMWH) enoxaparin in a population after hip or knee joint replacement.

Source: Thromboprophylaxis 28. 11. 2023

Články časopisu Cholesterol metabolism disturbances and statin therapy in elderly patients

Author of the article: P. Vyroubal Source: Geriatrie a Gerontologie | 2/2013 1. 5. 2013

News Metamizole vs. Tramadol in Postoperative Analgesia

Metamizole and tramadol are well-known analgesics that have been used in practice for a long time. Interesting insights into these substances were provided by the studies presented below. Spanish doctors evaluated the efficacy and safety of metamizole compared to tramadol in postoperative analgesia after abdominal hysterectomy. German researchers were interested in the possibility of applying a combination of these drugs in an analgesic regime controlled by the patient.

Source: Analgesia 19. 4. 2021

Články časopisu HELLP syndrome complicated by liver rupture –⁠ case report

Author of the article: M. Součková, R. Pilka, T. Malý, M. Procházka, J. Frančáková, V. Lattová, K. Horváthová Source: Česká gynekologie | 3/2014 18. 6. 2014