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News What is the significance of hormones in the pathophysiology of migraine?

Migraine is a complex neurovascular disease characterized by the dysfunction of the nociceptive trigeminovascular system in its pathophysiology. Its prevalence is 2-3 times higher in women than in men. The cause of this difference has not yet been fully elucidated, but it appears that the fluctuation of ovarian hormone levels and its influence on CGRP plays an important role. The following article summarizes findings on the hormonal influence of migraine and also discusses new prophylactic drugs –⁠ anti-CGRP antibodies.

Source: Migraine 27. 7. 2020

News Interactive Case Study: Use of Cannabis Extract for Local Treatment of Neuropathic Pain

We have been using cannabis for pain treatment for several years. We also have good experiences with it in difficult-to-control symptoms of neuropathic pain, as illustrated in the following case study. Until recently, our patients only used cannabis orally or via vaporization. With the availability of cannabis extracts, a new option has emerged –⁠ local therapy.

Source: Medical Cannabis 19. 6. 2024

News Is it possible to extend the life of diabetics thanks to modern treatment?

People aged 60 with type 2 diabetes are estimated to live on average 6-7 years less compared to their peers without a diabetes diagnosis. However, clinical study results suggest that modern therapy can prevent these lost years.

Source: Diabetes 29. 4. 2022

Články časopisu Risk faktors for development of knee and hip joint osteoarthritis for patients with total endoprosthesis indicated

Author of the article: M. Holubová, M. Čapková, L. Jirásková, K. Šoukalová Source: Česká revmatologie | 1/2019 25. 6. 2019

News More Patients Will Now Have Access to Incontinence Aids

Since December of last year, new rules have been in effect for the prescription of medical aids prescribed through vouchers, including aids for urine collection and voiding. The new rules are governed by the current wording of Act No. 48/1997 Coll., on Public Health Insurance, which also includes a new categorization tree (Appendix No. 3 to the Act).

Source: Incontinence 3. 3. 2020

News Impact of Prophylaxis on Reducing the Risk of Neurological Problems Associated with Bleeding in Hemophilia A

Bleeding can also cause complications in the nervous system of hemophiliacs. The authors of the work presented below discuss the significance of prophylactic administration of factor VIII coagulation concentrates, specifically concerning neurological complications related to bleeding.

Source: Hemophilia 14. 4. 2022

News Continuous Infusion of Tiapride in the Treatment of Hyperactive Delirium –⁠ Case Study

Spanish authors recently published a case study of a young man with pharmacologically unmanageable agitation delirium following multiple injuries from a traffic accident, which resolved within 3 days with continuous infusion of tiapride.

Source: Geriatric Patient 27. 2. 2020

Články časopisu Lung cancer prevention and prevention programs

Author of the article: Lubomír Tulinský Source: Časopis lékařů českých | 4/2023 19. 9. 2023

News Use of Tiapride in the Treatment of Behavioral Disorders in Geriatric Patients

Hand in hand with the increasing number of people reaching an older age, there is also a rise in the occurrence of dementia. It affects the lives of patients and their families in many ways. A significant problem can be behavioral disorder, which needs to be treated adequately and promptly to prevent issues such as injuries.

Source: Geriatric Patient 15. 9. 2020

Články časopisu Palliative care in nephrology

Author of the article: Barbora Szonowská Source: Časopis lékařů českých | 1/2018 19. 3. 2018

News Factors Influencing the Occurrence of Prosthetic Stomatitis in Patients with Complete Denture

Dental dentures are removable replacements made for partial or complete loss of teeth. Quality denture treatment is a long-lasting process in which oral hygiene and denture hygiene play a key role.

Source: Optimal Care of Dentures 18. 12. 2020

News Efficacy and Safety of Single-Application Hyaluronic Acid in Osteoarthritis Therapy

Causal therapy for osteoarthritis does not yet exist. Patients suffering from progressive joint disease are thus dependent on symptomatic medications that alleviate symptoms and partially slow the progression of osteoarthritis. An essential role in therapy is played by viscosupplementation in the form of intra-articular application of hyaluronic acid (HA). Currently, 3rd generation preparations intended for single application are preferred due to their efficiency and safety.

Source: Osteoarthritis 6. 11. 2020

News What a General Practitioner Needs to Know About Gliflozins

The revolutionary benefits of gliflozins have completely changed the perspective on the choice of pharmacotherapy for diabetes. They have attracted not only diabetologists but also cardiologists and nephrologists after the favorable effects of this group of drugs on heart failure and renal functions were demonstrated even in patients without diabetes. Dapagliflozin and empagliflozin were subsequently included in recommendations for the treatment of heart failure regardless of the presence of diabetes. Dapagliflozin has also been approved for the treatment of patients with chronic kidney disease.

Source: Diabetes 22. 3. 2023

News Effect of Nuclear Magnetic Resonance Therapy in Patients with Osteoarthritis

Osteoarthritis represents the most common joint disease in adults, with its incidence and prevalence increasing with age. With the overall aging of the population, it is becoming a significant medical as well as social problem. Due to the growing number of cases, new modalities are being sought for current therapeutic procedures, including nuclear magnetic resonance therapy, whose effect has been verified by an extensive clinical study.

Source: Treatment of the Musculoskeletal System 21. 2. 2020

News How does Benzalkonium Chloride and Prostaglandins Affect Meibomian Gland Epithelial Cells?

Benzalkonium chloride is commonly used in eye drops intended for glaucoma treatment due to its preservative effect. However, in recent years, it has been shown to cause damage to both superficial and deeper eye tissues and also provoke other difficulties. The study presented below examined its effect on the epithelium of the Meibomian glands.

Source: Treatment of Glaucoma 31. 3. 2021