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Články časopisu Prenatal growth curves of the Czech population

Author of the article: P. Polášková, A. Kuběna, P. Calda Source: Česká gynekologie | 4/2014 1. 8. 2014

News Thrombocytopenia Following mRNA Vaccination Against SARS-CoV-2

In connection with the administration of mRNA-based vaccines against the SARS-CoV-2 coronavirus, cases of secondary immune thrombocytopenia (ITP) have been described. A commentary published by a large team of authors in the American Journal of Hematology described a series of cases of low platelet counts identified within 2 weeks of vaccination. The data was obtained from the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), the Department of Health and Human Services (HHS), and the Vaccine Adverse Event Reporting System (VAERS), as well as through direct communication with patients and their physicians.

Source: Immune Thrombocytopenia 20. 5. 2021

Články časopisu Liver disease at alpha-1-antitrypsin deficiency

Author of the article: L. Husová, M. Dastych jr., E. Kunertová, P. Husa, K. Dvořák, M. Votava Source: Vnitřní lékařství | 1/2005 15. 1. 2005

News Benefit of Adding Erdosteine to Maintenance Treatment of COPD

Erdosteine is a mucoactive drug with anti-inflammatory, antioxidant, and anti-adhesive effects against bacteria, commonly used in the treatment of chronic obstructive pulmonary disease (COPD). In August 2022, another post-hoc analysis of the RESTORE study was published, evaluating the impact of its addition to COPD maintenance treatment on the incidence and severity of exacerbations and quality of life in patients with GOLD2 and GOLD3 grade bronchial obstruction.

Source: Cough Therapy 1. 11. 2022

News Long-term survival of a 50-year-old man with metastatic pancreatic cancer on a combination of nal-IRI + 5-FU/LV in 2nd line treatment −⁠ case study

A recently published case study from the Czech Republic describes a patient with progression of pancreatic cancer following surgical treatment and adjuvant chemotherapy, who achieved a one-year survival with good quality of life on a combination of nal-IRI + 5-FU/LV after the failure of gemcitabine + nab-paclitaxel in the 1st line of palliative treatment.

Source: Treatment of Gastrointestinal Carcinomas 3. 6. 2024

News Stabilization of Liver Metastases of CRC with Trifluridine/Tipiracil in 3rd Line Therapy –⁠ Case Study

We present a case study of a man born in 1944 who underwent resection of the rectosigmoid for multiple adenocarcinomas in February 2016. Subsequently discovered liver metastases were managed with several lines of palliative therapy in combination with repeated surgical resections. Trifluridine/tipiracil administered in the 3rd line represents a well-tolerated oral treatment for this patient, on which he achieved disease stabilization.

Source: Treatment of Gastrointestinal Carcinomas 10. 1. 2022

News Experience with Proton Radiotherapy for Anal Canal Carcinoma in Real Czech Practice

Radiotherapy has the potential to achieve complete tumor regression in patients with anal carcinoma, representing an effective alternative to radical surgery. However, it is associated with significant acute and late toxicity. Proton radiotherapy has shown better dose distribution in dosimetric studies compared to conventional photon therapy. What are the experiences with this treatment modality in real practice?

Source: Proton Radiotherapy 16. 10. 2023

News Vaccination Against COVID-19 in Patients Treated With Anticoagulants

Canadian professional societies and the National Health Service (NHS) in the United Kingdom recommend COVID-19 vaccination even for patients treated with anticoagulants. The benefit of vaccination in these patients significantly outweighs the risk of hematoma associated with intramuscular injection. The recommendation applies to both warfarin and direct oral anticoagulants (DOACs).

Source: Anticoagulant Treatment 11. 10. 2021

News Current Recommendations for Using SGLT2 Inhibitors in Patients with Renal or Cardiovascular Risk

Type 2 diabetes mellitus (DM2) is a serious chronic metabolic disease whose prevalence has been increasing in recent years. Currently, diabetics make up approximately 8−10% of the population. The therapy is traditionally focused primarily on suppressing the development and progression of diabetic complications, but modern antidiabetics have also brought other unprecedented benefits. The following text summarizes the role of gliflozins in the pharmacotherapy of DM2 in light of current recommendations.

Source: Heart Failure 20. 8. 2021

Články časopisu Peritoneal Carcinomatosis of Gastric Origin –⁠ Treatment Possibilities

Author of the article: David Hoskovec, Zdeněk Krška, Petr Dytrych, Michal Vočka Source: Klinická onkologie | 5/2019 14. 10. 2019

News Psychiatry of Transitional Age −⁠ An Important Area That Has Not Yet Received Much Attention

Three-quarters of psychiatric disorders develop before the age of 25, with up to half of these disorders appearing before the age of 16. The period of so-called emerging adulthood thus represents a key phase in psychiatry. Unfortunately, due to the separate development of child and adult psychiatry, this area has not yet received sufficient attention, and so-called transitional psychiatry is still in its infancy.

Source: Modern Treatment of Schizophrenia 19. 5. 2022

News Change in Release of Medication Pradaxa

Dear Doctor,
We would like to inform you that from April 1, 2021, based on the decision of the State Institute for Drug Control (SÚKL), the release of the medication (LP) Pradaxa (dabigatran-etexilate) 150 and 110 mg in the indication “Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation” will be changed to first-line treatment.

Source: Anticoagulant Treatment 31. 3. 2021

Články časopisu Prenatal diagnosis of Noonan syndrome in fetuses with increased nuchal translucency and a normal karyotype

Author of the article: M. Matyášová, Z. Dobšáková, M. Hiemerová, J. Kadlecová, D. Nikulenkov Grochová, E. Popelínská, E. Svobodová, P. Vlašín Source: Česká gynekologie | 3/2019 24. 4. 2019

News Multimodal Treatment of Prostate Cancer in a Patient with Exceptionally Long Overall Survival −⁠ Case Report

A recently published case study by Romanian authors presents a rare instance of long-term survival (15 years) in a patient with locoregional prostate cancer that later metastasized. The case illustrates the possibilities offered by currently available modern treatment modalities.

Source: Oncological Treatment 26. 10. 2023

Články časopisu Risk of thrombosis in association with oral contraceptive use from hematologist΄s point of view

Author of the article: Petr Dulíček, Eva Ivanová, Petr Sadílek, Martin Beránek Source: Praktická gynekologie | 4/2013 13. 12. 2013