Authors:
A. Hušek 1; Š. Erbertová 1; S. Popov 1; J. Šedý 2-4; M. Vaculová 5; P. Libánský 5
Authors‘ workplace:
1. LF UK, Praha
1; Klinika zubního lékařství LF UP a FN Olomouc
2; Ústav anatomie, 2. LF UK, Praha
3; Vysoká škola tělesné výchovy a sportu PALESTRA, spol. s r. o.
4; III. chirurgická klinika 1. LF UK a FN Motol, Praha
5
Published in:
Rozhl. Chir., 2025, roč. 104, č. 11, s. 492-494.
Category:
Original articles
doi:
https://doi.org/10.48095/ccrvch2025492
Overview
Introduction: Primary hyperparathyroidism (PHPT) is most commonly caused by a solitary parathyroid adenoma. The relationship between parathyroid hormone (PTH) levels and adenoma size remains unclear.
Methods: A retrospective analysis of 377 PHPT patients who underwent surgery at Third Department of Surgery, First Faculty of Medicine, Charles University and Motol University Hospital (2022–2023). Adenoma volume was calculated as an ellipsoid. The correlation between PTH and adenoma volume was assessed using regression analysis.
Results: A weak to moderate correlation was found (R = 0.315; P < 0.001). Linear regression showed that a 1 pmol/L increase in PTH corresponded to an average adenoma volume increase of 104 mm³.
Conclusion: Preoperative PTH levels partially correlate with adenoma volume, but their predictive value is limited.
Keywords:
adenoma – primary hyperparathyroidism – parathyroidectomy – parathormone
Sources
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