Synchronous liver metastases of rectal cancer and the possibility of simultaneous resection
Authors:
M. Zatloukal 1; V. Procházka 1; L. Ostřížková 2; V. Válek 3; Z. Kala 1; I. Penka 1
Authors‘ workplace:
Chirurgická klinika Fakultní nemocnice Brno a Lékařské fakulty Masarykovy univerzity
1; Interní a hematoonkologická klinika Fakultní nemocnice Brno a Lékařské fakulty Masarykovy univerzity
2; Klinika radiologie a nukleární medicíny Fakultní nemocnice Brno a Lékařské fakulty Masarykovy univerzity
3
Published in:
Rozhl. Chir., 2019, roč. 98, č. 10, s. 394-398.
Category:
Review
Overview
Treatment of metastatic rectal cancer and liver metastases continues to pose a major challenge. Synchronous liver metastases are present in up to one fifth of patients diagnosed with rectal carcinoma. Multidisciplinary cooperation is essential for determination of the consequent diagnostic and therapeutic plan. Only tight collaboration of experts from different medical fields allows for optimal timing of various medical procedures leading to a maximal benefit for the patient. Given the complexity of the problem, different specific methods and combinations thereof are applied in the course of the therapy, making the design of straightforward guidelines impossible. Since open surgery is complicated by the vastly distant locations of the rectum and liver, minimally invasive approach brings more perspectives in simultaneous surgery. A novel possibility of robotic and/or laparoscopic surgery performed by two teams is currently being developed. Despite the progress in surgical technology, optimal strategy has not yet been established.
Keywords:
rectal cancer – synchronous metastases – simultaneous resection
Sources
1. Národní onkologický registr (NOR) | ÚZIS ČR. Available from: https://www.uzis.cz/registry-nzis/nor (accessed 14 Jun 2019).
2. Adam R, de Gramont A, Figueras J, et al. Managing synchronous liver metastases from colorectal cancer: a multidisciplinary international consensus. Cancer Treat Rev. 2015;41:729–41. doi:10.1016/j.ctrv.2015.06.006.
3. Oxenberg J, Papenfuss W, Esemuede I, et al. Multidisciplinary cancer conferences for gastrointestinal malignancies result in measureable treatment changes: a prospective study of 149 consecutive patients. Ann Surg Oncol. 2015;22:1533–9. doi:10.1245/s10434-014-4163-y.
4. Ejaz A, Semenov E, Spolverato G, et al. Synchronous primary colorectal and liver metastasis: impact of operative approach on clinical outcomes and hospital charges. HPB (Oxford) 2014;16:1117–26. doi:10.1111/hpb.12302.
5. van der Pool AE, de Wilt JH, Lalmahomed ZS, et al. Optimizing the outcome of surgery in patients with rectal cancer and synchronous liver metastases. Br J Surg. 2010;97:383–90. doi:10.1002/bjs.6947.
6. MERCURY Study Group. Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. BMJ 2006;333:779. doi:10.1136/bmj.38937.646400.55.
7. Burdan F, Sudol-Szopinska I, Staroslawska E, et al. Magnetic resonance imaging and endorectal ultrasound for diagnosis of rectal lesions. Eur J Med Res. 2015;20:4. doi:10.1186/s40001-014-0078-0.
8. Glynne-Jones R, Wyrwicz L, Tiret E, et al. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29:iv263. doi:10.1093/annonc/mdy161.
9. Balyasnikova S, Brown G. Optimal imaging strategies for rectal cancer staging and ongoing management. Curr Treat Options Oncol. 2016;17:32. doi:10.1007/s11864-016-0403-7.
10. Huebner RH, Park KC, Shepherd JE, et al. A meta-analysis of the literature for whole-body FDG PET detection of recurrent colorectal cancer. J Nucl Med. 2000;41:1177–89.
11. Nicholson BD, Shinkins B, Pathiraja I, et al. Blood CEA levels for detecting recurrent colorectal cancer. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD011134.pub2.
12. Lehmann K, Rickenbacher A, Weber A, et al. Chemotherapy before liver resection of colorectal metastases: friend or foe? Ann Surg. 2012;255:237–47. doi:10.1097/SLA.0b013e3182356236.
13. Vandeweyer D, Neo EL, Chen JW, et al. Influence of resection margin on survival in hepatic resections for colorectal liver metastases. HPB (Oxford) 2009;11:499. doi:10.1111/j.1477-2574.2009.00092.x
14. Are C, Gonen M, Zazzali K, et al. The impact of margins on outcome after hepatic resection for colorectal metastasis. Ann Surg. 2007;246:295–300. doi:10.1097/SLA.0b013e31811ea962.
15. Belghiti J, Ogata S. Assessment of hepatic reserve for the indication of hepatic resection. J Hepatobiliary Pancreat Surg. 2005;12:1–3. doi:10.1007/s00534-004-0951-2.
16. Lambert LA, Colacchio TA, Barth RJ. Interval hepatic resection of colorectal metastases improves patient selection. Arch Surg. 2000;135:473–9; discussion 479−80.
17. Clancy C, O’Leary DP, Burke JP, et al. A meta-analysis to determine the oncological implications of conversion in laparoscopic colorectal cancer surgery. Colorectal Dis. 2015;17:482–90. doi:10.1111/codi.12875.
18. Montedori A, Cirocchi R, Farinella E, et al. Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev. 2010. doi:10.1002/14651858.CD006878.pub2
19. Meleagros L, Varty PP, Delrio P, et al. Influence of temporary faecal diversion on long-term survival after curative surgery for colorectal cancer. Br J Surg. 1995;82:21–5. doi:10.1002/bjs.1800820108
20. Vogt P, Raab R, Ringe B, et al. Resection of synchronous liver metastases from colorectal cancer. World J Surg. 1991;15:62–7.
21. Thelen A, Jonas S, Benckert C, et al. Simultaneous versus staged liver resection of synchronous liver metastases from colorectal cancer. Int J Colorectal Dis. 2007;22:1269–76. doi:10.1007/s00384-007-0286-.y.
22. Reddy SK, Pawlik TM, Zorzi D, et al. Simultaneous resections of colorectal cancer and synchronous liver metastases: a multi-institutional analysis. Ann Surg Oncol. 2007;14:3481–91. doi:10.1245/s10434-007-9522-5.
23. Nakajima K, Takahashi S, Saito N, et al. Predictive factors for anastomotic leakage after simultaneous resection of synchronous colorectal liver metastasis. J Gastrointest Surg. 2012;16:821–7. doi:10.1007/s11605-011-1782-5.
24. van der Poel MJ, Tanis PJ, Marsman HA, et al. Laparoscopic combined resection of liver metastases and colorectal cancer: a multicenter, case-matched study using propensity scores. Surg Endosc. 2019;33:1124–30. doi:10.1007/s00464-018-6371-1.
25. Ali SM, Pawlik TM, Rodriguez-Bigas MA, et al. Timing of surgical resection for curative colorectal cancer with liver metastasis. Ann Surg Oncol. 2018;25:32–7. doi:10.1245/s10434-016-5745-7.
26. Silberhumer GR, Paty PB, Temple LK, et al. Simultaneous resection for rectal cancer with synchronous liver metastasis is a safe procedure. Am J Surg. 2015;209:935–42. doi:10.1016/j.amjsurg.2014.09.024
27. Gavriilidis P, Sutcliffe RP, Hodson J, et al. Simultaneous versus delayed hepatectomy for synchronous colorectal liver metastases: a systematic review and meta-analysis. HPB (Oxford) 2018;20:11–9. doi:10.1016/j.hpb.2017.08.008.
28. Abelson JS, Michelassi F, Sun T, et al. Simultaneous resection for synchronous colorectal liver metastasis: The new standard of care? J Gastrointest Surg. 2017;21:975–82. doi:10.1007/s11605-017-3422-1.
29. Viganò L, Karoui M, Ferrero A, et al. Locally advanced mid/low rectal cancer with synchronous liver metastases. World J Surg. 2011;35:2788–95. doi:10.1007/s00268-011-1272-7.
30. Sabbagh C, Cosse C, Ravololoniaina T, et al. Oncological strategies for middle and low rectal cancer with synchronous liver metastases. Int J Surg. 2015;23:186–93. doi:10.1016/j.ijsu.2015.08.034.
31. Alexandrescu S, Diaconescu A, Ionel Z, et al. Comparative analysis between simultaneous resection and staged resection for synchronous colorectal liver metastases – a single center experience on 300 consecutive patients. Chirurgia (Bucur) 2017;112:278–88. doi:10.21614/chirurgia.112.3.278.
32. Muangkaew P, Cho JY, Han H-S, et al. Outcomes of simultaneous major liver resection and colorectal surgery for colorectal liver metastases. J Gastrointest Surg. 2016;20:554–63. doi:10.1007/s11605-015-2979-9.
33. Abitabile P, Hartl U, Lange J, et al. Radiofrequency ablation permits an effective treatment for colorectal liver metastasis. Eur J Surg Oncol. 2007;33:67–71. doi:10.1016/j.ejso.2006.10.040.
Labels
Surgery Orthopaedics Trauma surgeryArticle was published in
Perspectives in Surgery
2019 Issue 10
Most read in this issue
- Therapy of liver cysts – experience of the Department of Surgery, University Hospital in Pilsen 2009−2018
- Repopulation of decellularized pig scaffolds: Promising approach for liver tissue engineering
- Comparison of surgical intervention to Cyberknife® radiotherapy in the treatment of liver malignancies
- Radiofrequency ablation of colorectal liver metastases