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Synovial sarcoma of the liver – case report
Authors: J. Zajak; P. Hladík; R. Lischke
Authors‘ workplace: III. chirurgická klinika 1. LF UK a FNM, přednosta: prof. MUDr. R. Lischke, PhD.
Published in: Rozhl. Chir., 2015, roč. 94, č. 2, s. 78-81.
Category: Case Report
Overview
Synovial sarcoma is malignant mesenchymal fuso-cellular tumor with variable epithelial differentiation. We present the rare case of young female patient with primary synovial sarcoma of the liver. Molecular diagnosis was done by detection of SYT/SSX fusion transcript. Patients with sarcoma should be treated only in high specialized centres.
Key words:
synovial sarcoma of the liver
Sources
1. Drozenová J, Povýšil C, Tvrdík D, et al. Primární synoviální sarkom ledviny – popis dvou případů. Čes-slov Patol 2008;1 : 20−2.
2. Kawai A, Woodruff J, Murray FB, et al. SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. N Engl J Med 2004;338 : 153−60.
3. Tvrdík D, Povýšil C, Svatošová J, et al. Molecular diagnosis of synovial sarcoma: RT-PCR detection of SYT-SSX1/2 fusion transcripts in paraffin-embedded tissue. Med Sci Monit 2005;11 : 1−7.
4. Xiong B, Chen M, Ye F, et al. Primary monophasic synovial sarcoma of the liver in a 13-year-old boy. Pediatr Dev Pathol 2013;16 : 353−6.
5. Holla P, Hafez GR, Slukvin I, et al. Pathol Res Pract. Synovial sarcoma, a primary liver tumor-a case report. 2006;202 : 385−7.
6. Fletcher CDM, Bridge, JA, Hogendoorn PCW, et al. World Health Organization classification of tumours of soft tissue and bone. 4th ed. IARC Press, Lyon 2013.
7. ESMO/ European Sarcomas Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012 : 92−9.
8. Žaloudík J. Chirurgické aspekty léčby sarkomů měkkých tkání. Onkologie 2010;4 : 297−301.
Labels
Surgery Orthopaedics Trauma surgery
Article was published inPerspectives in Surgery
2015 Issue 2-
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