Serological survey and vaccination against viral hepatitis A in health care providers at the Clinic of Infectious Diseases in Ostrava
Authors:
L. Rožnovský 1; A. Kloudová 2; J. Dlhý 3; I. Lochman 2; M. Kovalská 4
Authors‘ workplace:
Infekční klinika FNsP a ZSF OU, Ostrava
1; Odbor imunologie a alergologie, Zdravotní ústav, Ostrava
2; Odbor epidemiologie, KHS Královéhradeckého kraje, Hradec Králové
3; Infekční klinika FNsP, Ostrava
4
Published in:
Epidemiol. Mikrobiol. Imunol. 54, 2005, č. 3, s. 129-136
Overview
Study objective:
The health care providers of the Clinic of Infectious Diseases in Ostrava were screened for immunity to hepatitis A virus (HAV) in an attempt to provide vaccination against hepatitis A to non-immune persons.
Study subjects and Methods:
A cohort of 101 health care providers of the Clinic of Infectious Diseases, i.e. 10 physicians, 56 nurses and 35 nursing auxiliaries, were screened. Total anti-HAV antibodies were determined by ELISA and the subjects not reaching the protective level of anti-HAV antibodies were considered as non-immune. Vaccination against hepatitis A was recommended to all of the non-immune persons.
Results:
Immunity to HAV was detected in 41 (41 %) of 101 screened subjects. Immunity was increasing with age, being found in 8 % of subjects under 40 years of age and 59 % of older subjects, in 2 (20 %) physicians, 23 (41 %) nurses and 16 and nursing auxiliaries. Vaccination of 58 nonimmune subjects was conducted without complications.
Conclusion:
The prevalence rates of total anti-HAV antibodies in health care providers of the Clinic of Infectious Diseases showed a continuing upward trend with age and were practically the same as in the community.
Key words:
viral hepatitis A – immunity – prevalence – health care providers – vaccination.
Labels
Hygiene and epidemiology Medical virology Clinical microbiologyArticle was published in
Epidemiology, Microbiology, Immunology
2005 Issue 3
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