Necrobiosis Lipoidica


Authors: J. Nováková
Authors‘ workplace: Kožní oddělení FN Ostrava a LF OU Ostrava, vedoucí pracoviště prim. MUDr. Yvetta Vantuchová, Ph. D.
Published in: Čes-slov Derm, 96, 2021, No. 2, p. 59-69
Category: Reviews (Continuing Medical Education)

Overview

Necrobiosis lipoidica je chronické granulomatózní onemocnění kůže, které bývá sdruženo s diabetem nebo glukózovou intolerancí. Etiologie nemoci není jasná, nejčastěji se zvažuje zásadní role mikroangiopatie. Typickým projevem jsou červenohnědé ploché papuly na přední straně bérců splývající v plošná atrofická ložiska s teleangiektaziemi. Komplikací může být vznik ulcerace v ložisku. Diagnóza se stanoví podle klinického obrazu a případného histologického vyšetření. Léčba necrobiosis lipoidica je neuspokojivá nejsou k dispozici přijaté léčebné postupy. Článek poskytuje současný přehled léčebných metod této nemoci.

Keywords:

necrobiosis lipoidica – etiopathogenesis – diagnostics – treatment – diabetes mellitus


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