Syndrom střevní pseudoobstrukce u nemocného s akutní polyradikuloneuritidou
Authors:
K. Šimková 1; L. Ungermann 2; E. Ehler 1,3; I. Štětkářová 4
Authors‘ workplace:
Department of Neurology Pardubice Regional Hospital, Czech Republic
1; Radiodiagnostic Department of the Pardubice Regional Hospital, Czech Republic
2; Department of Neurology, Faculty of Health Studies, University of Pardubice, Czech Republic
3; Department of Neurology, Third Faculty of Medicine, Královské Vinohrady University Hospital, Prague, Czech Republic
4
Published in:
Cesk Slov Neurol N 2026; 89(3): 199-201
Category:
Letter to Editor
doi:
https://doi.org/10.48095/cccsnn2026199
...
Sources
1. Underhill J, Munding E, Hayden D. Acute colonic pseudo-obstruction and volvulus: pathophysiology, evaluation, and treatment. Clin Colon Rectal Surg 2021; 34 (4): 242–250. doi: 10.1055/s-0041-1727195.
2. Wells CI, O‘Grady G, Bissett IP. Acute colonic pseudo-obstruction: a systematic review of aetiology and mechanisms. World J Gastroenterol 2017; 23 (30): 5634–5644. doi: 10.3748/wjg.v23.i30.5634.
3. Arthur T, Burgess A. Acute colonic pseudo-obstruction. Clin Colon Rectal Surg 2022; 35 (3): 221–226. doi: 10.1055/s-0041-1740044.
4. Vanek P, Urban O, Falt P. Percutaneous endoscopic cecostomy for management of Ogilvie’s syndrome: a case series and literature Review with an update on current guideline. [online]. Available from: https: //doi.org/10.1007/s00464-023-10281-w.
5. Pérez-Lara JL, Santana Y, Hernández-Torres J et al. Acute colonic pseudo-obstruction caused by dexmedetomidine: a case report and literature review. Am J Case Rep 2019; 20 : 278–284. doi: 10.12659/AJCR.913645.
6. Haj M, Haj M, Rockey DC. Ogilvie‘s syndrome: management and outcomes. Medicine (Baltimore) 2018; 97 (27): e11187. doi: 10.1097/MD.0000000000011187.
7. Man BL, Fu YP. Intestinal pseudo-obstruction as a presenting symptom of Guillain-Barré syndrome. BMJ Case Rep 2014; 2014: bcr2014205155. doi: 10.1136/bcr-2014-205155.
8. Ramirez R, Zuckerman MJ, Hejazi RA et al. Treatment of acute colonic pseudo-obstruction with tegaserod. Am J Med Sci 2010; 339 (6): 575–576. doi: 10.1097/MAJ.0b013e3181db6b95.
9. Sahu TA. An atypical descending variant of guillain-barré syndrome with bulbar palsy, autonomic instability, and delayed colonic pseudo-obstruction: a case report. Cureus 2025; 17 (10): e95802. doi: 10.7759/cureus.95802.
10. Luo L, Chen L, Li J et al. Case report: successful treatment of severe Guillain-Barré syndrome with paralytic ileus as a presenting symptom by intensive immunotherapy. Front Immunol 2025; 16 : 1435817. doi: 10.3389/fimmu.2025.1435817.
11. Diagnosis is primarily based on imaging findings. Caecal dilatation exceeding 12 cm is associated with a high risk of ischaemia and perforation [1]. In our case, significant dilatation was observed without progression to perforation.
12. Management of ACPO is primarily conservative. Neostigmine is effective and typically produces a rapid response within 5–30 minutes. Additional prokinetic agents include metoclopramide, erythromycin, and cisapride. Prucalopride, a selective 5-HT4 receptor agonist, represents a newer therapeutic option. Endoscopic or surgical interventions are reserved for refractory cases or complications. Recurrence rates range from 18% to 33%.
Labels
Paediatric neurology Neurosurgery NeurologyArticle was published in
Czech and Slovak Neurology and Neurosurgery
2026 Issue 3
Most read in this issue
- 100 years of the Czech Department of Neurology, Charles UniversityThe Henner school
- Intestinal pseudo-obstruction syndrome in a patient with acute polyradiculoneuritis
- Perinatal ischemic stroke – a review of current knowledge
- Epilepsy surgery in children operated on before 3 years of age – experience of the Motol epilepsy center