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What should a surgeon known about genetic background of thyroid cancer

Czech version

Authors: P. Bavor 1;  B. Peková 2;  V. Sýkorová 2;  B. Bendlová 2;  J. Hoch 1
Authors‘ workplace: Chirurgická klinika 2. lékařské fakulty Univerzity Karlovy a Fakultní nemocnice Motol, Praha 1;  Oddělení molekulární endokrinologie, Endokrinologický ústav, Praha 2
Published in: Rozhl. Chir., 2020, roč. 99, č. 11, s. 481-486.
Category: Review

Overview

Thyroid cancer is the most common endocrine malignancy, the treatment is multidisciplinary and multimodal. Thyroid tumors are heterogeneous in origin, morphology, biological behavior and therapeutic options. Substantial advances in diagnostic methods for  thyroid cancer have led to detection of earlier stages of the disease that have the possibility of targeted therapeutic treatment and improved patient prognosis. In addition to surgical treatment, hormonal suppression and radioiodine therapy, targeted molecular therapy, which requires genetic testing, has come to the fore in recent decades. In the summary, we present an overview of current knowledge on the genetic background of individual types of thyroid carcinomas and the possibilities of therapeuticintervention.

Keywords:

tumors of thyroid gland − genetics

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Labels
Surgery Orthopaedics Trauma surgery
History of thyroid surgery
Chirurgie štítné žlázy a příštítných tělísek
Papillary thyroid microcarcinoma and papillary thyreoid cancer at the Department of Surgery, EUC Clinic Zlín
Retrosternal goiter
Differentiated thyroid microcarcinoma − current perspective
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Endoscopic approaches in head and neck endocrine surgery − introduction of TOETVA (TransOral Endoscopic Thyroidectomy by Vestibular Approach) into clinical use at the Department of Surgery of the University Hospital in Brno
Zakladatel německé neurochirurgie a prvního samostatného neurochirurgického časopisu Wilhelm Tönnis (1898–1978) – dílo v kontextu doby
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Perspectives in Surgery

Issue 11
2020 Issue 11
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