Narcolepsy in childhood – our experiences
Authors:
V. Kučeravá; L. Remeň; P. Ďurdík; A. Ďurdíková; S. Suroviaková; P. Bánovčin
Authors‘ workplace:
Klinika detí a dorastu, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave, Univerzitná nemocnica Martin, Slovensko
Published in:
Čes-slov Pediat 2021; 76 (6): 313-319.
Category:
Case Report
Overview
Narcolepsy is a chronic neurological disease characterized by a disorder of sleep cycle regulation. It is classified as hypersomnia in the classification of sleep disorders. The incidence of this disease is estimated at 1:2000, but it is often under diagnosed in childhood. There is no etiology currently fully elucidated, hypocretin deficiency is thought. Diagnosis is based on detailed sleep history, standard all-night videopolysomnography examination with multiple sleep latency test (MSLT) and cerebrospinal fluid hypocretin determination. Disease due to its nature leads to a reduced quality of life in patients.
We present case reports of three patients from the Department of Children and Adolescents of University Hospital in Martin with newly diagnosed narcolepsy based on the above procedures, two patients also underwent collection of cerebrospinal fluid to determine hypocretin levels with a positive result.
Keywords:
Narcolepsy – polysomnography – children – hypersomnia – MSLT – hypocretin
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Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2021 Issue 6
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