Metastases of the malignant melanoma to myocardium – a rare cause of the heart failure
Authors:
L. Mihaličová 1; A. Gavel 2; M. Novačeková 3; P. Bališ 4; S. Dražilová 1
Authors‘ workplace:
Oddelenie vnútorného lekárstva, Nemocnica Poprad a. s., Primár: MUDr. Sylvia Dražilová, PhD.
1; Súdnolekárske a patologicko-anatomícké pracovisko ÚDZS, Poprad
Primár: MUDr. Lukáš Hamerlik
2; Patologická anatómia, Nemocnica Poprad a. s.
Primár: MUDr. Mária Novačeková
3; Ústav normálnej a patologickej fyziológie SAV, Bratislava
Vedúci: RNDr. Iveta Bernátová, DrSc.
4
Published in:
Prakt. Lék. 2017; 97(6): 274-278
Category:
Case Report
Overview
The malignant melanoma is an aggressive disease with a high potential of spreading metastases to any organ, heart included. We are presenting a patient, by whom a generalisation of the heart disease was manifested by a heart failure sixteen years after extirpation of malignant melanoma. The diagnose was made after patient´s death. Studies of necroptic material show that malignant melanoma creates metastases to heart in 50–64% of the cases. However, because of the default of specific clinical cases and the limited possibilities of using imaging techniques the diagnose is mostly declared after the death of the patient. That is why it is necessary in patients with history taking of malignant melanoma to think about tumour generalisation by every cardiac symptom.
Keywords:
liver cirrhosis – hearth failure – melanoma – metastasis
Sources
1. Aerts BR, Kock MC, Kofflard MJ, et al. Cardiac metastasis of malignant melanoma: a case report. Neth Heart J 2014; 22(1): 39–41.
2. Demondion P, Garot J, Bouvier E, et al. Left ventricular metastasis from ocular melanoma: a new, rare, and unusual pathway? Ann Thorac Surg 2013; 96(1): e13–14.
3. Glancy DL, Roberts WC. The heart in malignant melanoma. A study of 70 autopsy cases. Am J Cardiol 1968; 21: 555–571.
4. Gulati G, Sharma S, Kothari SS, et al. Comparison of echo and MRI in the imaging evaluation of intracardiac masses. Cardiovasc Intervent Radiol 2004; 27(50): 459–469.
5. Cheruvu B, Cheruvu P, Boyars M. An unusual case of metastasis to the left side of the heart: a case report. J Med Case Reports 2011; 5: 23.
6. Judge JM, Tillou JD, Slingluff CL Jr, et al. Surgical management of the patient with metastatic melanoma to the heart. J Card Surg 2013; 28(2): 124–128.
7. Malouf JF, Thompson RC, Maples WJ, et al. Diagnosis of right atrial metastatic melanoma by transesophageal echocardiographic-guided transvenous biopsy. Mayo Clin Proc 1996; 71: 1167–1170.
8. Onan B, Onan IS, Polat B, et al. Surgical resection of solitary metastasis of malignant melanoma to the right atrium. Tex Heart Inst J 2010; 37: 598–601.
9. Ozyuncu N, Sahin M, Altin T, et al. Cardiac metastasis of malignant melanoma: a rare cause of complete atrioventricular block. Europace 2006; 8(7): 545–548.
10. Pinho T, Rodrigues-Pereira P, Araujo V, et al. Cardiac metastasis of melanoma as first manifestation of disease. Rev Port Cardiol 2009; 28: 633–639.
11. Savoia P, Fierro MT, Zaccagna A, et al. Metastatic melanoma of the heart. J Surg Oncol 2000; 75(3): 203–207.
12. Tas F, Mudun A, Kirma C. Cardiac involvement in melanoma: a case report and review of the literature. J Cancer Res Ther 2010; 6: 359–361.
13. Villa A, Eshja E, Dallavalle S, et al. Cardiac metastases of melanoma as first manifestation of the disease. J Radiol Case Rep 2014; 8(4): 8–15.
14. Wood A, Markovic SN, Best PJ, et al. Metastatic malignant melanoma manifesting as an intracardiac mass. Cardiovasc Pathol 2010; 19(3): 153–157.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2017 Issue 6
Most read in this issue
- Inoperable form of alveolar echinococcosis of the liver
- Follow-up and long-term care in the Czech Republic – an overview of the current state and changes in bed capacity from the National Health Information System
- Dilaceration of eye caused by a fire cracker explosion
- Study of new anticoagulants – partial results