Management of acute anaphylaxis in clinical practice in the context of the guidelines

Czech version

Authors: Ch. P. Cmorej; M. Nesvadba; R. Babeľa; O. Slowik; R. Didič
Authors‘ workplace: Vysoká škola zdravotníctva a sociálnej práce sv. Alžbety, Ústav zdravotníckych disciplín, Bratislava
Published in: Epidemiol. Mikrobiol. Imunol. 66, 2017, č. 1, s. 30-38
Category: Review Article

Overview

Anaphylaxis is a rapidly progressing, life-threatening allergic reaction that needs rapid diagnosis and treatment. Recent research has brought new information about the increasing incidence of anaphylaxis. Nevertheless, the prevalence and incidence of anaphylaxis are difficult to estimate due to the lack of consensus on the definition of anaphylaxis, differences between the population groups analysed, and use of different data collection methods. The most common triggers of anaphylaxis are food allergens, insect stings, and drugs. The serum tryptase level serves as a diagnostic indicator of anaphylaxis. In patients with normal serum tryptase levels, other inflammatory mediators need to be considered. Epinephrine is still the drug of choice for the therapy of severe anaphylaxis. The authors present new information about anaphylaxis from the recently published literature and/or guidelines

KEYWORDS:
anaphylaxis – epinephrine – guidelines – histamine – tryptase

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Article was published in

Epidemiology, Microbiology, Immunology

2017 Issue 1