Next-generation sequencing
Authors:
Eva Froňková
Authors‘ workplace:
Laboratoř molekulární genetiky CLIP, Klinika dětské hematologie a onkologie 2. LF UK a FN Motol, Praha
Published in:
Čes.-slov. Patol., 49, 2013, No. 3, p. 129-132
Category:
Reviews Article
Overview
Next generation or massive parallel sequencing (MPS) is a rapidly advancing method in molecular genetics that will bring significant changes in the personalized medicine field. In this review we briefly describe major types of MPS, including whole-genome, -exome, -transcriptome and amplicon sequencing. We also present an overview of the advantages, drawbacks and possible applications of sequencing technologies available in the Czech Republic.
Keywords:
massive parallel sequencing – next generation sequencing – whole-genome – exome – transcriptome – amplicon sequencing
Sources
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
2013 Issue 3
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