Are you medic and you dont have account?
|Authors: Zámečník M.1, Chlumská A.2,3, Ondriaš F.1
|Authors - sphere of activity: 1Alpha Medical Pathology, s.r.o., Bratislava, Slovak Republic;
2Šikl`s Department of Pathology, Faculty Hospital, Charles University, Pilsen, Czech Republic;
3Laboratory of Surgical Pathology, Pilsen, Czech Republic
|Article: Čes.-slov. Patol., 48, 2012, No. 2, p. 94-96|
|Category: Original Articles|
|Number of articles displayed: 132x|
An unusual case of ganglioneuroma with perineural cell differentiation is presented. The tumor was removed from the mediastinum in a 34-year-old male patient. Histologically, it contained neuroid bundles of bland spindle cells, scattered ganglion cells, and some foci of adipocytic metaplasia. Immunohistochemically, the tumor showed expected expressions of S100 protein, neurofilament protein and calretinin. In addition, many spindle cells were positive for perineural cell markers EMA, claudin-1, and GLUT-1. These cells were often arranged in an organoid fashion around the schwannoid bundles. This case indicates that the cells of ganglioneuroma can mature simultaneously towards both Schwann cell and perineural cell phenotypes.
ganglioneuroma – perineurioma – EMA – claudin-1 – GLUT-1
A majority of primary diseases for which orthotopic
The view on the role of donor-specific antibodies
Endometrial carcinoma (EC) is the most common malignancy
Pyloric gland adenoma is a rare neoplasm with
Background: As up to 60 % of triple