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Czecho-Slovak Pathology

Molecular pathology of lung cancer in routine diagnostic practice: 2017 update

Molecular pathology of lung cancer in routine diagnostic practice: 2017 update

The group of non–small cell lung carcinomas includes tumors that are variable at the clinical, histopathological and molecular levels. Advances in the understanding of...

Full article   Czecho-Slovak Pathology Issue: 4/2017

Specialization: Toxicology Forensic medical examiner Anatomical pathology
Hamartoma of mature cardiac myocytes. <br>Autopsy case report

Hamartoma of mature cardiac myocytes.
Autopsy case report

Hamartoma of mature cardiac myocytes (HMCM) is a rare benign pseudoneoplastic myocardial lesion. We describe a case of 39-year-old Bulgarian woman living in the Czech Republic...

Full article   Czecho-Slovak Pathology Issue: 4/2017

Specialization: Toxicology Forensic medical examiner Anatomical pathology
What´s new in Ewing-like sarcoma family? Soft tissue and bone sarcomas with CIC/BCOR rearrangement. Review of the literature and first personal experience

What´s new in Ewing-like sarcoma family? Soft tissue and bone sarcomas with CIC/BCOR rearrangement. Review of the literature and first personal experience

The literature is reviewed regarding of a rare molecularly defined group of sarcomas with rearrangement of both CIC and BCOR genes, which were originally placed into the EWSR1wt...

Full article   Czecho-Slovak Pathology Issue: 4/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Molecular mechanisms of primary and secondary resistance, molecular-genetic features and characteristics of KIT/PDGFRA non-mutated GISTs

Molecular mechanisms of primary and secondary resistance, molecular-genetic features and characteristics of KIT/PDGFRA non-mutated GISTs

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Most of them arise due to activating mutations in KIT (75 – 85...

Full article   Czecho-Slovak Pathology Issue: 4/2017

Specialization: Toxicology Forensic medical examiner Anatomical pathology
Isolated infectious endocarditis of the pulmonary valve: a case report

Isolated infectious endocarditis of the pulmonary valve: a case report

Isolated infectious endocarditis of the pulmonary valve is a rare condition and represents 1,5-2% of all cases of infectious endocarditis. We present a case of a 37year-old...

Full article   Czecho-Slovak Pathology Issue: 3/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Lymph node metastasis of Merkel cell carcinoma without known cutaneous primary - case report

Lymph node metastasis of Merkel cell carcinoma without known cutaneous primary - case report

Merkel cell carcinoma is a rare cutaneous tumor with an aggressive clinical course. In most cases it is associated with Merkel cell polyomavirus infection. Exceptionally, the...

Full article   Czecho-Slovak Pathology Issue: 3/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Changes of the WHO classification of lymphoid neoplasms in the context of the 2016 revision

Changes of the WHO classification of lymphoid neoplasms in the context of the 2016 revision

As a result of increasing knowledge, the validity of any tumour classification could not be unlimited. The aim of this article is to review the most important changes in the WHO...

Full article   Czecho-Slovak Pathology Issue: 3/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Changes of the WHO classification of myeloid neoplasms in the context of the 2016 revision

Changes of the WHO classification of myeloid neoplasms in the context of the 2016 revision

Continual progress of knowleges in hematopathology and genetics of hematologic tumors requires actualisation of widely accepted and presently used WHO classification of myeloid...

Full article   Czecho-Slovak Pathology Issue: 3/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Giant cell-rich lesions of bone and their differential diagnosis

Giant cell-rich lesions of bone and their differential diagnosis

Giant cell-rich lesions form a heterogeneous group of reactive and truly neoplastic processes with diverse clinical presentation and biological behavior. Common to all of them...

Full article   Czecho-Slovak Pathology Issue: 2/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology
Myxoid tumors of soft tissues

Myxoid tumors of soft tissues

Myxoid tumours of soft tissue represent a heterogeneous spectrum of lesions with variable biological behaviour, from completely benign to highly aggressive malignancies. Myxoid...

Full article   Czecho-Slovak Pathology Issue: 2/2017

Specialization: Anatomical pathology Forensic medical examiner Toxicology