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Invasive myoepithelial carcinoma ex pleomorphic adenoma of the major salivary gland: two case reports

Invasive myoepithelial carcinoma ex pleomorphic adenoma of the major salivary gland: two case reports

Background: Myoepithelial carcinoma (MEC) is a rare salivary gland tumor. Its long-term prognosis remains unknown because of the paucity of reported cases with long-term follow...

Full article   BMC Cancer Issue: 827/2016

Specialization: Clinical oncology Paediatric clinical oncology
Epidemiological study of <i>HER-2</i> mutations among EGFR wild-type lung adenocarcinoma patients in China

Epidemiological study of HER-2 mutations among EGFR wild-type lung adenocarcinoma patients in China

Background: Human epidermal growth factor receptor (HER)-2 is a driver gene in non-small cell lung cancer (NSCLC). The present study evaluated the mutation rate of HER-2 within...

Full article   BMC Cancer Issue: 828/2016

Specialization: Paediatric clinical oncology Pneumology and ftiseology Clinical oncology
Selumetinib suppresses cell proliferation, migration and trigger apoptosis, G1 arrest in triple-negative breast cancer cells

Selumetinib suppresses cell proliferation, migration and trigger apoptosis, G1 arrest in triple-negative breast cancer cells

Background: Triple-negative breast cancer (TNBC) has aggressive progression with poor prognosis and ineffective treatments. Selumetinib is an allosteric, ATP-noncompetitive...

Full article   BMC Cancer Issue: 818/2016

Specialization: Clinical oncology Paediatric clinical oncology
Cervical and breast cancer screening uptake among women with serious mental illness: a data linkage study

Cervical and breast cancer screening uptake among women with serious mental illness: a data linkage study

Background: Breast and cancer screening uptake has been found to be lower among women with serious mental illness (SMI). This study aims to corroborate these findings in the UK...

Full article   BMC Cancer Issue: 819/2016

Specialization: Clinical oncology Paediatric clinical oncology
Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial

Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial

Background: Solid tumors, such as hepato-pancreato-biliary cancer, develop tumor hypoxia with tumor growth. Despite advances in surgery, a majority of these patients are in an...

Full article   BMC Cancer Issue: 812/2016

Sentinel lymph node biopsy after neoadjuvant chemotherapy for breast cancer: retrospective comparative evaluation of clinically axillary lymph node positive and negative patients, including those with axillary lymph node metastases confirmed by fine needle aspiration

Sentinel lymph node biopsy after neoadjuvant chemotherapy for breast cancer: retrospective comparative evaluation of clinically axillary lymph node positive and negative patients, including those with axillary lymph node metastases confirmed by fine needle aspiration

Background: To evaluate the accuracy of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) in breast cancer patients with axillary lymph node (ALN...

Full article   BMC Cancer Issue: 808/2016

CT guided cryoablation for locally recurrent or metastatic bone and soft tissue tumor: initial experience

CT guided cryoablation for locally recurrent or metastatic bone and soft tissue tumor: initial experience

Background: Historically, local control of recurrent sarcomas has been limited to radiotherapy when surgical re-resection is not feasible. For metastatic carcinomas to the bone...

Full article   BMC Cancer Issue: 798/2016

Disseminated carcinomatosis of the bone marrow from pancreatic cancer: a case report

Disseminated carcinomatosis of the bone marrow from pancreatic cancer: a case report

Background: Most cases of disseminated carcinomatosis of the bone marrow (DCBM) arise from gastric cancer. DCBM from pancreatic cancer is very rare. We herein present a case of...

Full article   BMC Cancer Issue: 801/2016

Successful treatment of gemcitabine-induced acute interstitial pneumonia with imatinib mesylate: a case report

Successful treatment of gemcitabine-induced acute interstitial pneumonia with imatinib mesylate: a case report

Background: Gemcitabine is currently the standard chemotherapy for the adjuvant treatment of pancreatic cancer. This chemotherapeutic agent is generally well-tolerated...

Full article   BMC Cancer Issue: 793/2016