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Reconsidering the associations between self-reported alcohol use disorder and mental health problems in the light of co-occurring addictions in young Swiss men


Autoři: Simon Marmet aff001;  Joseph Studer aff001;  Mélissa Lemoine aff001;  Véronique S. Grazioli aff001;  Nicolas Bertholet aff001;  Gerhard Gmel aff001
Působiště autorů: Addiction Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland aff001;  Addiction Switzerland, Lausanne, Switzerland aff002;  Centre for Addiction and Mental Health, Toronto, Canada aff003;  University of the West of England, Frenchay Campus, Bristol, United Kingdom aff004
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222806

Souhrn

Background

Alcohol use disorder (AUD) is known to co-occur with other addictions, as well as with mental health problems. However, the effects of other addictions co-occurring with AUD on mental health problems were rarely studied and not considering them may bias estimates of the association between AUD and mental health problems. This study investigated which role co-occurring addictions play for the cross-sectional associations between self-reported AUD and mental health problems.

Method

Participants were 5516 young Swiss men (73.0% of those that gave written informed consent) who completed a self-report questionnaire. Using short screening questionnaires, we assessed three substance use disorders (alcohol, cannabis and tobacco), seven behavioural addictions (internet, gaming, smartphone, internet sex, gambling, work, exercise) and four mental health problems (major depression, bipolar disorder, attention deficit hyperactivity disorder (ADHD) and social anxiety disorder). Differences in the proportions of mental health problems were tested using logistic regressions between (1) participants with no AUD and AUD, (2) participants with no AUD and AUD alone and (3) participants with no AUD and AUD plus at least one co-occurring addiction.

Results

Overall, (1) participants with AUD had higher proportions of major depression (Odds ratio (OR [95% confidence interval]) = 3.51 [2.73, 4.52]; ADHD (OR = 3.12 [2.41, 4.03]); bipolar disorder (OR = 4.94 [3.38, 7.21]) and social anxiety (OR = 2.21 [1.79, 2.73])) compared to participants with no AUD. Considering only participants with AUD alone compared to participants with no AUD (2), differences in proportions were no longer significant for major depression (OR = 0.83 [0.42, 1.64]), bipolar disorder (OR = 1.69 [0.67, 4.22]), social anxiety (OR = 1.15 [0.77, 1.73]) and ADHD (OR = 1.65 [1.00, 2.72]) compared to participants with no AUD. In contrast, (3) proportions of mental health problems were considerably higher for participants with AUD plus at least one other addiction when compared to participants with no AUD, with OR’s ranging from 2.90 [2.27, 3.70] for social anxiety, 4.03 [3.02, 5.38] for ADHD, 5.29 [4.02, 6.97] for major depression to 6.64 [4.44, 9.94] for bipolar disorder.

Conclusions

AUD was associated with all four measured mental health problems. However, these associations were mainly due to the high proportions of these mental health problems in participants with AUD plus at least one co-occurring addiction and only to a lesser degree due to participants with AUD alone (i.e. without any other co-occurring addictions). Hence, estimates of the association between AUD and mental health problems that do not consider other addictions may be biased (i.e. overestimated). These findings imply that considering addictions co-occurring with AUD, including behavioural addictions, is important when investigating associations between AUD and mental health problems, and for the treatment of AUD and co-morbid disorders.

Klíčová slova:

Addiction – ADHD – Alcoholism – Behavioral addiction – Bipolar disorder – Internet – Mental health and psychiatry – Gambling addiction


Zdroje

1. Gmel G, Kuendig H, Notari L, Gmel C. Suchtmonitoring Schweiz—Konsum von Alkohol, Tabak und illegalen Drogen in der Schweiz im Jahr 2016. Lausanne: Sucht Schweiz; 2017.

2. Marmet S, Gmel G. Suchtmonitoring Schweiz–Alkoholkonsumstörungen im Jahr 2013. Lausanne: Sucht Schweiz; 2014.

3. Sussman S, Lisha N, Griffiths M. Prevalence of the addictions: a problem of the majority or the minority? Evaluation & the health professions. 2011;34(1):3–56. doi: 10.1177/0163278710380124 20876085

4. Konkolÿ Thege B, Hodgins DC, Wild TC. Co-occurring substance-related and behavioral addiction problems: A person-centered, lay epidemiology approach. J Behav Addict. 2016;5(4):614–22. doi: 10.1556/2006.5.2016.079 27829288

5. Schluter MG, Hodgins DC, Wolfe J, Cameron Wild T. Can one simple questionnaire assess substance‐related and behavioural addiction problems? Results of a proposed new screener for community epidemiology. Addiction. 2018. doi: 10.1111/add.14166 29357188

6. Morisano D, Babor TF, Robaina KA. Co-occurrence of substance use disorders with other psychiatric disorders: Implications for treatment services. Nordic studies on alcohol and drugs. 2014;31(1):5–25. doi: 10.2478/nsad-2014-0002

7. Boden JM, Fergusson DM. Alcohol and depression. Addiction. 2011;106(5):906–14. doi: 10.1111/j.1360-0443.2010.03351.x 21382111

8. van Emmerik-van Oortmerssen K, van de Glind G, van den Brink W, Smit F, Crunelle CL, Swets M, et al. Prevalence of attention-deficit hyperactivity disorder in substance use disorder patients: A meta-analysis and meta-regression analysis. Drug & Alcohol Dependence. 2012;122(1):11–9. doi: 10.1016/j.drugalcdep.2011.12.007 22209385

9. Di Florio A, Craddock N, Van den Bree M. Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates. European Psychiatry. 2014;29(3):117–24. doi: 10.1016/j.eurpsy.2013.07.004 24075633

10. Schneier FR, Foose TE, Hasin DS, Heimberg RG, Liu S-M, Grant BF, et al. Social anxiety disorder and alcohol use disorder co-morbidity in the National Epidemiologic Survey on Alcohol and Related Conditions. Psychological medicine. 2010;40(6):977–88. doi: 10.1017/S0033291709991231 20441690

11. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author: American Psychiatric Publishing; 2013.

12. Kardefelt-Winther D, Heeren A, Schimmenti A, van Rooij A, Maurage P, Carras M, et al. How can we conceptualize behavioural addiction without pathologizing common behaviours? Addiction. 2017;112(10):1709–15. doi: 10.1111/add.13763 28198052; PubMed Central PMCID: PMC5557689.

13. Bhalla IP, Stefanovics EA, Rosenheck RA. Clinical epidemiology of single versus multiple substance use disorders: Polysubstance use disorder. Medical Care. 2017;55:S24–S32. doi: 10.1097/MLR.0000000000000731 28806363

14. MacLean RR, Sofuoglu M, Rosenheck R. Tobacco and alcohol use disorders: Evaluating multimorbidity. Addictive behaviors. 2018;78:59–66. doi: 10.1016/j.addbeh.2017.11.006 29127785

15. Skinstad AH, Swain A. Comorbidity in a clinical sample of substance abusers. The American journal of drug and alcohol abuse. 2001;27(1):45–64. doi: 10.1081/ada-100103118 11373036

16. Moss HB, Goldstein RB, Chen CM, Yi H-Y. Patterns of use of other drugs among those with alcohol dependence: Associations with drinking behavior and psychopathology. Addictive behaviors. 2015;50:192–8. doi: 10.1016/j.addbeh.2015.06.041 26151585

17. Connor JP, Gullo MJ, Chan G, Young RM, Hall WD, Feeney GF. Polysubstance use in cannabis users referred for treatment: drug use profiles, psychiatric comorbidity and cannabis-related beliefs. Frontiers in psychiatry. 2013;4:79. doi: 10.3389/fpsyt.2013.00079 23966956

18. Andreas JB, Lauritzen G, Nordfjærn T. Co-occurrence between mental distress and poly-drug use: a ten year prospective study of patients from substance abuse treatment. Addictive behaviors. 2015;48:71–8. doi: 10.1016/j.addbeh.2015.05.001 26004857

19. Hakansson A, Schlyter F, Berglund M. Associations between polysubstance use and psychiatric problems in a criminal justice population in Sweden. Drug and alcohol dependence. 2011;118(1):5–11. doi: 10.1016/j.drugalcdep.2011.02.014 21419580

20. Smith GW, Farrell M, Bunting BP, Houston JE, Shevlin M. Patterns of polydrug use in Great Britain: Findings from a national household population survey. Drug and alcohol dependence. 2011;113(2–3):222–8. doi: 10.1016/j.drugalcdep.2010.08.010 20863629

21. White A, Chan GC, Quek L-H, Connor JP, Saunders JB, Baker P, et al. The topography of multiple drug use among adolescent Australians: Findings from the National Drug Strategy Household Survey. Addictive Behaviors. 2013;38(4):2068–73. doi: 10.1016/j.addbeh.2013.01.001 23403274

22. Le Strat Y, Ramoz N, Gorwood P. In alcohol-dependent drinkers, what does the presence of nicotine dependence tell us about psychiatric and addictive disorders comorbidity? Alcohol & Alcoholism. 2010;45(2):167–72. doi: 10.1093/alcalc/agp094 20089545

23. Gmel G, Akre C, Astudillo M, Bähler C, Baggio S, Bertholet N, et al. The Swiss Cohort Study on Substance Use Risk Factors–Findings of two waves. SUCHT. 2015;61(4):251–62. doi: 10.1024/0939-5911.a000380

24. Studer J, Baggio S, Mohler-Kuo M, Dermota P, Gaume J, Bertholet N, et al. Examining non-response bias in substance use research–Are late respondents proxies for non-respondents? Drug and alcohol dependence. 2013;132(1–2):316–23. doi: 10.1016/j.drugalcdep.2013.02.029 23535061

25. Studer J, Mohler-Kuo M, Dermota P, Gaume J, Bertholet N, Eidenbenz C, et al. Need for informed consent in substance use studies–harm of bias? Journal of Studies on Alcohol and Drugs. 2013;74:931–40. doi: 10.15288/jsad.2013.74.931 24172121

26. Bech P, Rasmussen NA, Olsen LR, Noerholm V, Abildgaard W. The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity. Journal of Affective Disorders. 2001;66(2–3):159–64. doi: 10.1016/s0165-0327(00)00309-8 11578668

27. Bech P, Timmerby N, Martiny K, Lunde M, Soendergaard S. Psychometric evaluation of the Major Depression Inventory (MDI) as depression severity scale using the LEAD (Longitudinal Expert Assessment of All Data) as index of validity. BMC psychiatry. 2015;15(1):190. doi: 10.1186/s12888-015-0529-3 26242577

28. Cortina JM. What is coefficient alpha? An examination of theory and applications. Journal of applied psychology. 1993;78(1):98.

29. Taber KS. The use of Cronbach’s alpha when developing and reporting research instruments in science education. Research in Science Education. 2018;48(6):1273–96.

30. Tavakol M, Dennick R. Making sense of Cronbach's alpha. International journal of medical education. 2011;2:53. doi: 10.5116/ijme.4dfb.8dfd 28029643

31. Hirschfeld RMA, Williams JBW, Spitzer RL, Calabrese JR, Flynn L, Keck PEJ, et al. Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire. American Journal of Psychiatry. 2000;157(11):1873–5. doi: 10.1176/appi.ajp.157.11.1873 11058490.

32. Weber Rouget B, Gervasoni N, Dubuis V, Gex-Fabry M, Bondolfi G, Aubry J-M. Screening for bipolar disorders using a French version of the Mood Disorder Questionnaire (MDQ). Journal of Affective Disorders. 2005;88(1):103–8. doi: 10.1016/j.jad.2005.06.005 16054228

33. Kessler RC, Adler L, Ames M, Demler O, Faraone S, Hiripi E, et al. The World Health Organization adult ADHD self-report scale (ASRS): A short screening scale for use in the general population. Psychological Medicine. 2005;35(02):245–56. doi: 10.1017/S0033291704002892 15841682

34. Dalrymple K, Martinez J, Tepe E, Young D, Chelminski I, Morgan T, et al. A clinically useful social anxiety disorder outcome scale. Comprehensive Psychiatry. 2013;54(7):758–65. doi: 10.1016/j.comppsych.2013.02.006 23642634

35. Knight JR, Wechsler H, Kuo M, Seibring M, Weitzman ER, Schuckit MA. Alcohol abuse and dependence among U.S. college students. Journal of Studies on Alcohol. 2002;63:263–70. doi: 10.15288/jsa.2002.63.263 12086126

36. Grant BF, Dawson DA, Stinson FS, Chou PS, Kay W, Pickering R. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and alcohol dependence. 2003;71(1):7–16. doi: 10.1016/s0376-8716(03)00070-x 12821201

37. Marmet S, Studer J, Bertholet N, Grazioli VS, Daeppen JB, Gmel G. Interpretation of DSM-5 alcohol use disorder criteria in self-report surveys may change with age. A longitudinal analysis of young Swiss men. Addiction Research & Theory. 2019. doi: 10.1080/16066359.2018.1547817

38. Annaheim B, Scotto TJ, Gmel G. Revising the Cannabis Use Disorders Identification Test (CUDIT) by means of Item Response Theory. International Journal of Methods in Psychiatric Research. 2010;19(3):142–55. doi: 10.1002/mpr.308 20812291

39. Adamsom SJ, Sellman JD. A prototype screening instrument for cannabis use disorder: the Cannabis Use Disorders Identification Test (CUDIT) in an alcohol-dependent clinical sample. Drug and Alcohol Review. 2003;22(3):309–15. doi: 10.1080/0959523031000154454 15385225

40. Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom K-O. The Fagerström Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. British Journal of Addiction. 1991;86(9):1119–27. doi: 10.1111/j.1360-0443.1991.tb01879.x 1932883

41. Fagerstrom KO, Heatherton TF, Kozlowski L. Nicotine addiction and its assessment. Ear Nose Throat J. 1992;69(11):763–7.

42. Meerkerk GJ, Van Den Eijnden RJJM, Vermulst AA, Garretsen HFL. The Compulsive Internet Use Scale (CIUS): Some psychometric properties. Cyber Psychology & Behavior. 2009;12(1):1–6. doi: 10.1089/cpb.2008.0181 19072079

43. Meerkerk GJ, van den Eijnden RJ, Franken I, Garretsen H. Is compulsive internet use related to sensitivity to reward and punishment, and impulsivity? Comput Hum Behav. 2010;26(4):729–35. doi: 10.1016/j.chb.2010.01.009

44. Lemmens JS, Valkenburg PM, Peter J. Development and validation of a game addiction scale for adolescents. Media Psychology. 2009;12(1):77–95. doi: 10.1080/15213260802669458

45. Kwon M, Kim D-J, Cho H, Yang S. The Smartphone Addiction Scale: Development and validation of a short version for adolescents. PLOS ONE. 2014;8(12):e83558. doi: 10.1371/journal.pone.0083558 24391787

46. Haug S, Paz Castro R, Kwon M, Filler A, Kowatsch T, Schaub MP. Smartphone use and smartphone addiction among young people in Switzerland. J Behav Addict. 2015;4(4):299–307. doi: 10.1556/2006.4.2015.037 26690625.

47. Delmonico D, Miller J. The Internet Sex Screening Test: A comparison of sexual compulsives versus non-sexual compulsives. Sexual and Relationship Therapy. 2003;18(3):261–76. doi: 10.1080/1468199031000153900

48. Carnes PJ, Delmonico DL, Griffin E. In the shadows of the net: Breaking free of compulsive online sexual behavior: Simon and Schuster; 2009.

49. Office of Alcoholism and Substance Abuse Services. DSM-IV Pathological Gambling Diagnostic Form n.d. [cited 2017 September 10]. Available from: http://www.oasas.ny.gov/gambling/documents/822dsmivforweb.pdf.

50. Andreassen CS, Griffiths MD, Hetland J, Pallesen S. Development of a work addiction scale. Scandinavian Journal of Psychology. 2012;53(3):265–72. doi: 10.1111/j.1467-9450.2012.00947.x 22490005

51. Terry A, Szabo A, Griffiths M. The exercise addiction inventory: A new brief screening tool. Addiction Research & Theory. 2004;12(5):489–99. doi: 10.1080/16066350310001637363

52. Midi H, Sarkar SK, Rana S. Collinearity diagnostics of binary logistic regression model. Journal of Interdisciplinary Mathematics. 2010;13(3):253–67.

53. Schuckit MA. Comorbidity between substance use disorders and psychiatric conditions. Addiction. 2006;101(s1):76–88. doi: 10.1111/j.1360-0443.2006.01592.x 16930163

54. Lieb R. Epidemiological perspectives on comorbidity between substance use disorders and other mental disorders. Co-occurring addictive and psychiatric disorders: Springer; 2015. p. 3–12.

55. Thapar A, Cooper M, Eyre O, Langley K. Practitioner review: what have we learnt about the causes of ADHD? Journal of Child Psychology and Psychiatry. 2013;54(1):3–16. doi: 10.1111/j.1469-7610.2012.02611.x 22963644

56. van Wamel A, van Rooijen S, Kroon H. Integrated treatment: The model and European experiences. Co-occurring Addictive and Psychiatric Disorders: Springer; 2015. p. 27–45.

57. Dom G, Moggi F. Toward a new model of care: Integrating mental health, substance use, and somatic care. Co-occurring Addictive and Psychiatric Disorders: Springer; 2015. p. 375–89.

58. Freimuth M, Waddell M, Stannard J, Kelley S, Kipper A, Richardson A, et al. Expanding the scope of dual diagnosis and co-addictions: Behavioral addictions. Journal of Groups in Addiction & Recovery. 2008;3(3–4):137–60. doi: 10.1080/15560350802424944

59. Griffiths MD, Demetrovics Z, Atroszko PA. Ten myths about work addiction. J Behav Addict. 2018:1–13. doi: 10.1556/2006.7.2018.05 29409339

60. Aarseth E, Bean AM, Boonen H, Colder Carras M, Coulson M, Das D, et al. Scholars’ open debate paper on the World Health Organization ICD-11 gaming disorder proposal. J Behav Addict. 2017;6(3):267–70. doi: 10.1556/2006.5.2016.088 28033714

61. Rumpf H-J, Brandt D, Demetrovics Z, Billieux J, Carragher N, Brand M, et al. Epidemiological Challenges in the Study of Behavioral Addictions: a Call for High Standard Methodologies. Current Addiction Reports. 2019:1–7.


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